NMNAT2 抗体
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北京 101111
Quick Overview for NMNAT2 抗体 (ABIN1169224)
抗原
See all NMNAT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-NMNAT2 (human), mAb (Nady-1)
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特异性
- Recognizes human NMNAT2.
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产品特性
- Monoclonal Antibody. Recognizes human NMNAT2. Isotype: Mouse IgG1kappa. Clone: Nady-1. Applications: ELISA, IHC, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer's disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human NMNAT2.
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亚型
- IgG1 kappa
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anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 208-307) antibody
NMNAT2 适用: 人 WB 宿主: 小鼠 Monoclonal 4E6 unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 131-146), (Intracellular) antibodyNMNAT2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (C-Term) antibodyNMNAT2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-302) antibodyNMNAT2 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2G8 unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-302) antibodyNMNAT2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) antibodyNMNAT2 适用: 人 ELISA, WB, IHC 宿主: 豚鼠 Polyclonal unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 1-153) antibodyNMNAT2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 208-307) antibodyNMNAT2 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2) (AA 131-146), (Intracellular) antibodyCarrier-free NMNAT2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- NMNAT2 (Nicotinamide Nucleotide Adenylyltransferase 2 (NMNAT2))
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别名
- NMNAT2
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背景
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Alternate Names/Synonyms: Nicotinamide Mononucleotide Adenylyltransferase 2, NMN Adenylyltransferase 2, NaMN Adenylyltransferase 2
Product Description: NMNAT2 catalyzes the formation of NAD+ from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form nicotinic acid mononucleotide (NaMN) as a substrate but with lower efficiency. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD+. Highly expressed in brain, in particular in cerebrum, cerebellum, occipital lobe, frontal lobe, temporal lobe and putamen. Also found in the heart, skeletal muscle, pancreas and islets of Langerhans. Has been shown to correlate with Alzheimer's disease in APPswe/PS1dE9 transgenic mice and delayed wallerian degeneration in cultured superior cervical ganglia (SCGs) from morphological changes, microtubule destruction and neurofilament degradation.
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UniProt
- Q9BZQ4
抗原
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