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NQO1 抗体

This anti-NQO1 antibody is a 小鼠 单克隆 antibody detecting NQO1 in WB 和 ELISA. Suitable for 人.
产品编号 ABIN1169222
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NQO1 抗体 (ABIN1169222)

抗原

See all NQO1 抗体
NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This NQO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

Skiny-1
  • 特异性

    Recognizes human NQO1. Detects a band of ~32 kDa by Western blot.

    交叉反应

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human NQO1.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

    别名

    NQO1

    背景

    NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

    UniProt

    Q3B792
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