NQO1 抗体
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北京 101111
Quick Overview for NQO1 抗体 (ABIN1169221)
抗原
See all NQO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- anti-NQO1 (human), mAb (Skiny-1)
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特异性
- Recognizes human NQO1. Detects a band of ~32 kDa by Western blot.
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产品特性
- Monoclonal Antibody. Recognizes human NQO1. Detects a band of ~32 kDa by Western blot. Isotype: Mouse IgG2akappa. Clone: Skiny-1. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human NQO1.
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亚型
- IgG2a kappa
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anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) antibody
NQO1 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 4D12 unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (C-Term) antibodyVerified NQO1 适用: 人, 大鼠 WB, ELISA, IHC, IF 宿主: 山羊 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (C-Term) antibodyNQO1 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-274) antibodyNQO1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 2-274) antibodyNQO1 适用: 人 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-274) antibodyNQO1 适用: 人 WB, ELISA, IP, IF, RNAi 宿主: 小鼠 Monoclonal 1E3-A6 unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-50) antibodyNQO1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 2-273) antibodyNQO1 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 2-274) antibodyNQO1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NAD(P)H Dehydrogenase, Quinone 1 (NQO1) (AA 1-274) antibodyNQO1 适用: 人 WB, ELISA, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4.
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储存液
- Without preservative
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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别名
- NQO1
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背景
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Alternate Names/Synonyms: NAD(P)H Dehydrogenase (Quinine) 1 (NQO1), Quinone Reductase 1 (QR1), DT-Diaphorase (DTD), Azoreductase, Phylloquinone Reductase, Menadione Reductase, Dioxin-inducible 1, Disphorase-4 (DIA4), NAD(P)H:Quinone Oxireductase, NAD(P)H:Quinone Oxidoreductase 1
Product Description: NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
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UniProt
- Q3B792
抗原
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