IDO1 抗体
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北京 101111
Quick Overview for IDO1 抗体 (ABIN1169197)
抗原
See all IDO1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human IDO. Detects a band of ~45 kDa by Western blot.
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交叉反应
- 人
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交叉反应 (详细)
- Other species not tested.
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human IDO.
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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别名
- IDO
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背景
- IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
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UniProt
- P14902
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途径
- Activated T Cell Proliferation
抗原
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