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IDO1 抗体

This anti-IDO1 antibody is a 小鼠 单克隆 antibody detecting IDO1 in WB, ELISA 和 IHC. Suitable for 人.
产品编号 ABIN1169197
发货至: 中国

Quick Overview for IDO1 抗体 (ABIN1169197)

抗原

See all IDO1 抗体
IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

适用

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宿主

  • 78
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小鼠

克隆类型

  • 69
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  • 1
单克隆

标记

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This IDO1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

克隆位点

ID 177
  • 特异性

    Recognizes human IDO. Detects a band of ~45 kDa by Western blot.

    交叉反应

    交叉反应 (详细)

    Other species not tested.

    过滤

    0.2 μm filtered

    免疫原

    Recombinant human IDO.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.

    有效期

    12 months
  • 抗原

    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

    别名

    IDO

    背景

    IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.

    UniProt

    P14902

    途径

    Activated T Cell Proliferation
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