IDO1 抗体
(5 references)Quick Overview for IDO1 抗体 (ABIN1169196)
抗原
See all IDO1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes human IDO. Detects a band of ~45 kDa by Western blot.
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交叉反应
- 人
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human IDO.
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anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibody
Verified IDO1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibodyIDO1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 4D2 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-403) antibodyIDO1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 小鼠 WB, ELISA, IHC, IF, FACS, IP, FM, MA 宿主: 小鼠 Monoclonal 2E2-6 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 1-100) antibodyIDO1 适用: 人, 小鼠 ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 304-403) antibodyIDO1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C5 unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (Internal Region) antibodyIDO1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) antibodyIDO1 适用: 小鼠 WB, ELISA, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Indoleamine 2,3-Dioxygenase 1 (IDO1) (AA 204-403) antibodyIDO1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
有效期
- 6 months
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: "Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity." in: Cancer research, Vol. 72, Issue 6, pp. 1407-15, (2012) (PubMed).
: "The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells." in: PLoS ONE, Vol. 6, Issue 5, pp. e19823, (2011) (PubMed).
: "Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells." in: Haematologica, Vol. 95, Issue 12, pp. 2022-30, (2010) (PubMed).
: "Functional alteration of the lymphoma stromal cell niche by the cytokine context: role of indoleamine-2,3 dioxygenase." in: Cancer research, Vol. 69, Issue 7, pp. 3228-37, (2009) (PubMed).
: "HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells." in: Blood, Vol. 109, Issue 8, pp. 3351-9, (2007) (PubMed).
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: "Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity." in: Cancer research, Vol. 72, Issue 6, pp. 1407-15, (2012) (PubMed).
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- IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
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别名
- IDO
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背景
- IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
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UniProt
- P14902
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途径
- Activated T Cell Proliferation
抗原
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