BAFF 抗体
Our Local Distributor
北京 101111
Quick Overview for BAFF 抗体 (ABIN1169145)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
原理
- anti-BAFF (human), mAb (2.81)
-
特异性
- Recognizes human BAFF.
-
产品特性
- Monoclonal Antibody. Recognizes human BAFF. Isotype: Rat IgG2b. Clone: 2.81. Applications: ELISA, IP. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
-
纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
-
纯度
- >95 % (SDS-PAGE)
-
免疫原
- HA-tagged human BAFF.
-
亚型
- IgG2b
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
-
有效期
- 12 months
-
-
- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
-
别名
- BAFF
-
背景
-
Alternate Names/Synonyms: BLyS, TALL-1, CD257, B Cell Activating Factor, TNFSF13B
Product Description: BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation. BAFF co-stimulates activated T cells. Increased levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren's syndrome, rheumatoid arthritis, multiple sclerosis and systemic lupus erythematosus (SLE). Furthermore, BAFF is found in inflammatory sites in which there is lymphoid neogenesis. BAFF levels are elevated in patients with multiple myeloma and B cell chronic lymphoid leukemia (B-CCL).
-
UniProt
- Q9Y275
-
途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
-