IL23A 抗体
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北京 101111
Quick Overview for IL23A 抗体 (ABIN1169135)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human IL-23p19.
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交叉反应
- 人
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过滤
- 0.2 μm filtered
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免疫原
- Recombinant human IL-23p19.
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亚型
- IgG2a
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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储存液
- Without preservative
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储存条件
- 4 °C,-20 °C
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储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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别名
- IL-23p19
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背景
- IL-23p19 associates with IL-12b to form the IL-23 interleukin, an heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 binds to an heterodimeric receptor complex composed of IL-12RB1 and IL-23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
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UniProt
- Q9NPF7
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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