(2 references)-
- 抗原 See all BTLA 抗体
- BTLA (B and T Lymphocyte Associated (BTLA))
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适用
- 人
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This BTLA antibody is un-conjugated
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应用范围
- ELISA, Flow Cytometry (FACS)
- 特异性
- Recognizes human BTLA.
- 交叉反应
- 人
- 纯化方法
- Purified from concentrated hybridoma tissue culture supernatant.
- 纯度
- >95 % (SDS-PAGE)
- 内毒素水平
- <0.001EU/μg purified protein.
- 免疫原
- Ectodomain of human BTLA fused to human IgG Fc.
- 克隆位点
- 6F4
- 亚型
- IgG1
- Top Product
- Discover our top product BTLA Primary Antibody
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anti-B and T Lymphocyte Associated (BTLA) antibody
BTLA 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 2E4 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 31-157) antibodyBTLA 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 5G1G10 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 179-289) antibodyBTLA 适用: 人 WB, ELISA, FACS, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 7H3E3 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 221-289) antibodyBTLA 适用: 人, 小鼠 WB, ELISA, FACS, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) antibodyBTLA 适用: 人 WB, FACS, IF 宿主: 小鼠 Monoclonal 2G2 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 101-150) antibodyBTLA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 30-183) antibodyBTLA 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B and T Lymphocyte Associated (BTLA) (AA 190-289) antibodyBTLA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4B8 unconjugated
anti-B and T Lymphocyte Associated (BTLA) (C-Term) antibodyBTLA 适用: 人 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- In PBS containing 10 % glycerol.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. - 有效期
- 12 months
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: "T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7286-96, (2009) (PubMed).
: "Unconventional ligand activation of herpesvirus entry mediator signals cell survival." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 15, pp. 6244-9, (2009) (PubMed).
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: "T cell intrinsic heterodimeric complexes between HVEM and BTLA determine receptivity to the surrounding microenvironment." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 11, pp. 7286-96, (2009) (PubMed).
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- 抗原
- BTLA (B and T Lymphocyte Associated (BTLA))
- 别名
- BTLA (BTLA 产品)
- 别名
- BTLA antibody, BTLA1 antibody, CD272 antibody, A630002H24 antibody, B and T lymphocyte associated antibody, BTLA antibody, Btla antibody
- 背景
- B and T lymphocyte associated (BTLA) is an Ig domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs. The herpes virus entry mediator (HVEM), a member of the TNF receptor (TNFR) superfamily, can act as a molecular switch that modulates T cell activation by propagating positive signals from the TNF-related ligand LIGHT (TNFR superfamily 14), or inhibitory signals through the Ig superfamily member BTLA. The binding site on HVEM for BTLA is conserved in the orphan TNF receptor UL144, present in human CMV. UL144 binds BTLA, but not LIGHT, and inhibits T cell proliferation, selectively mimicking the inhibitory cosignaling function of HVEM.
- UniProt
- Q7Z6A9
- 途径
- Cancer Immune Checkpoints
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