SIRT2 抗体
Our Local Distributor
北京 101111
Quick Overview for SIRT2 抗体 (ABIN1169092)
抗原
See all SIRT2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
特异性
- Recognizes human sirtuin 2. Detects a band of ~45 kDa by Western blot.
-
交叉反应
- 人
-
过滤
- 0.2 μm filtered
-
免疫原
- Recombinant human sirtuin 2.
-
亚型
- IgG2b
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
-
储存液
- Without preservative
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C. -
有效期
- 12 months
-
-
- SIRT2 (Sirtuin 2 (SIRT2))
-
别名
- Sirtuin 2
-
背景
- Sirtuin-2 is a NAD-dependent protein deacetylase, which deacetylates the 'Lys-40' of a-tubulin. It is involved in the control of mitotic exit in the cell cycle. Furthermore, a variety of age-associated diseases such as type 2 diabetes, obesity, osteoporosis, and Alzheimer's disease are associated with sirtuins. Selective inhibition of Sirtuin-2 achieves neuroprotection and identifies Sirtuin-2 to be a potential therapeutic avenue in Huntington's and Parkinson's disease.
-
UniProt
- Q8IXJ6
抗原
-