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Clusterin 抗体

The 兔 多克隆 anti-Clusterin antibody is suitable to detect Clusterin in samples from 小鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN1169057
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Clusterin 抗体 (ABIN1169057)

抗原

See all Clusterin (CLU) 抗体
Clusterin (CLU)

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Clusterin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 特异性

    Recognizes mouse clusterin. Detects a band of ~48 kDa by Western blot.

    交叉反应

    小鼠

    过滤

    0.2 μm filtered

    免疫原

    Recombinant mouse nuclear clusterin.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

    储存液

    Without preservative

    储存条件

    4 °C,-20 °C

    储存方法

    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.

    有效期

    6 months
  • 抗原

    Clusterin (CLU)

    别名

    Clusterin

    背景

    Clusterin shares homology with the small heat shock protein family of molecular chaperones. The mature secreted form of the protein is a glycosylated, 80- kDa disulfide-linked heterodimer of alpha and beta subunits (produced by internal cleavage). Clusterin is expressed in virtually all tissues and found in all fluids. It is involved in numerous physiological processes important for carcinogenesis and tumor growth, including apoptotic cell death, cell cycle regulation, DNA repair, cell adhesion, tissue remodeling, lipid transportation, membrane recycling, and immune system regulation. Clusterin also exists as a nuclear protein. The secreted form of Clusterin has extracellular chaperone and anti-apoptotic activities while the nuclear form acts as a proapoptotic factor.

    UniProt

    Q06890

    途径

    Apoptosis, Negative Regulation of intrinsic apoptotic Signaling
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