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APOE 抗体

APOE 适用: 人 WB, IP, IHC (p), IHC (fro), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN116547
发货至: 中国
  • 抗原 See all APOE 抗体
    APOE (Apolipoprotein E (APOE))
    适用
    • 101
    • 75
    • 56
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 101
    • 22
    • 14
    • 2
    山羊
    克隆类型
    • 105
    • 33
    多克隆
    标记
    • 58
    • 18
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    This APOE antibody is un-conjugated
    应用范围
    • 110
    • 58
    • 39
    • 39
    • 30
    • 24
    • 19
    • 12
    • 9
    • 8
    • 6
    • 5
    • 3
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    • 2
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    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This product has been prepared by Immunoaffinity chromatography using immobilized antigens followed by extensive cross-adsorption against other Apolipoproteins and human serum proteins to remove any unwanted specificities. Typically less than 1 % cross reactivity against other types of apoLipoprotein was detected by ELISA against purified standards. This antibody reacts with human Apolipoprotein E and has negligible cross-reactivity with Type A-1 A-II, B, C-I, C-II, C-III and J Apolipoproteins. Specific cross reaction of anti-Apolipoprotein antibodies with antigens from other species has not been determined. Non-specific cross reaction of anti-Apolipoprotein antibodies with other human serum proteins is negligible.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Apolipoprotein Type E was isolated from Human plasma by density gradient centrifugation followed by HPLC purification.
    Top Product
    Discover our top product APOE Primary Antibody
  • 应用备注
    Anti-apoLipoprotein antibodies have been used for indirect trapping ELISA for quantitationof antigen in serum using a standard curve, for immunoprecipitation and for westernblotting for highly sensitive qualitative analysis. Recommended dilutions: ELISA: 1/4,000-1/8,000Western blot: 1/500-1/2,000Immunohistochemistry: 1/50-1/200
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL (by UV absorbance at 280 nm)
    缓冲液
    0.125 M Sodium Borate, 0.075 M Sodium Chloride, 0.005 M EDTA, pH 8.0, containing 0.01 % Sodium Azide as preservtive
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquts) at -20 °C for longer.
  • 抗原
    APOE (Apolipoprotein E (APOE))
    别名
    Apolipoprotein E (Apo E) (APOE 产品)
    别名
    ad2 antibody, apoprotein antibody, im:7036787 antibody, wu:fb69a05 antibody, zgc:110064 antibody, apoe antibody, AI255918 antibody, AD2 antibody, LDLCQ5 antibody, LPG antibody, APOEA antibody, Apo-E antibody, apolipoprotein E antibody, apolipoprotein Ea antibody, apoe antibody, apoea antibody, Apoe antibody, APOE antibody
    背景
    Apolipoprotein E is essential for the normal catabolism of triglyceride rich lipoprotein constituents. The apolipoprotein E gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in Apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Mutations in the APOE gene confer susceptibility to Alzheimer's disease by affecting amyloid-beta deposition.Synonyms: Apo-E, ApoE
    基因ID
    348
    NCBI登录号
    NP_000032
    UniProt
    P02649
    途径
    Regulation of Cell Size, Lipid Metabolism
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