BAFF 抗体
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北京 101111
Quick Overview for BAFF 抗体 (ABIN116401)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Affinity chromatography.
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免疫原
- Highly pure (>98%) recombinant hBAFF.
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 116-278) antibody
TNFSF13B 适用: 人 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 6C3A2 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 221-309) antibodyTNFSF13B 适用: 人, 大鼠 ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 76-285) antibodyTNFSF13B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 1-285) antibodyTNFSF13B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 118-222) antibodyTNFSF13B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3G6 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 134-285) antibodyTNFSF13B 适用: 人 ELISA, FACS, ICC, IF 宿主: 小鼠 Monoclonal H4-C7 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 45-169) antibodyTNFSF13B 适用: 大鼠 WB, IHC, IP, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) antibodyTNFSF13B 适用: 人 WB, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1D6 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 16-44) antibodyTNFSF13B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B) (AA 265-285) antibodyTNFSF13B 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Neutralization. ELISA: To detect hBAFF by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hBAFF. Western Blot: To detect hBAFF by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hBAFF is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of > 0.2 mg/mL.
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缓冲液
- 0.5 X PBS, pH 7.4 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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别名
- CD257 / BAFF
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背景
- Members of the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF (for B cell Activating Factor belonging to the TNF Family), BLyS (for B Lymphocyte Stimulator), TALL1 (for TNF- and ApoL- related Leukocyte-expressed Ligand), and THANK (for TNF Homologue that Activate Apoptosis, NFkB and c-jun N-terminal Kinase). BAFF/BLyS was characterized as a B cell stimulator since it induced B cell proliferation and immunoglobulin secretion. Two receptors for BAFF were recently identified and designated TACI and BCMA. BAFF also signals through a third TNF receptor BAFFR/BR3. BAFF and its receptors are involved in the development of systemic lupus erythaematosus and other B cell associated autoimmune diseases. Like TNFa and TRAIL, THANK was shown to activate NF-kB and c-jun N terminal kinase (JNK) and to induce apoptosis. The human BAFF gene codes for a 285 amino acid type II transmembrane protein containing a 46 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 218 amino acid extracellular domain.Synonyms: B cell-activating factor, B lymphocyte stimulator, BAFF, BLYS, Dendritic cell-derived TNF-like molecule, TALL1, TNF- and APOL-related leukocyte expressed ligand 1, TNFSF13B, TNFSF20, Tumor necrosis factor ligand superfamily member 13B, ZTNF4
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基因ID
- 10673
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NCBI登录号
- NP_001139117
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UniProt
- Q9Y275
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
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