电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

IL-13 抗体

IL13 适用: 小鼠 WB, Func, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN116389
发货至: 中国
  • 抗原 See all IL-13 (IL13) 抗体
    IL-13 (IL13) (Interleukin 13 (IL13))
    适用
    • 82
    • 30
    • 26
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 72
    • 26
    • 17
    • 2
    • 2
    克隆类型
    • 76
    • 43
    多克隆
    标记
    • 68
    • 16
    • 9
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-13 antibody is un-conjugated
    应用范围
    • 85
    • 69
    • 32
    • 17
    • 16
    • 13
    • 13
    • 12
    • 10
    • 10
    • 10
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)
    特异性
    Reacts with Murine Interleukin 13.
    纯化方法
    Affinity chromatography.
    免疫原
    Highly purified (>98%) recombinant mouse IL-13
    Top Product
    Discover our top product IL13 Primary Antibody
  • 应用备注
    Neutralization. ELISA: (Indirect): To detect mIL-13 by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant mIL-13. (Sandwich): To detect mIL-13 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原
    IL-13 (IL13) (Interleukin 13 (IL13))
    别名
    Interleukin-13 / IL13 (IL13 产品)
    别名
    IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
    背景
    Human IL13 was originally identified by differential screening of an anti CD28 activated human peripheral blood mononuclear cell cDNA library as an induction specific novel cytokine. It was also isolated from cDNA libraries of human T cell clones using the murine IL13 (P600) cDNA as a probe. Human IL13, a pleiotropic cytokine, is produced by activated Th0, Th1 like, Th2 like, and CD8 T cells. The gene for human IL13 maps to chromosome 5 and is closely linked to the genes for IL3, IL4, IL5, and GMCSF. IL13 inhibits proinflammatory cytokine production and stimulates antibody production. It induces proliferation in the human pre myeloid cell line TF1. IL13 has multiple effects on the differentiation and functions of monocytes and macrophages. It suppresses cytotoxic functions and induces changes in the morphology of human monocytes and in the phenotype of human monocytes and B cells by upregulating MHC class II expression. IL13 will also decrease the production of nitric oxide by activated murine macrophages, leading to impaired parasiticidal activity. Human and mouse interleukin 13 share approximately 58 % amino acid sequence identity. Although human and mouse IL13 are equally active on human cells, human IL13 is much less active than mouse IL13 on mouse cells. Human IL13 and human IL4 also share approximately 30 % sequence homology and have similar biological functions.Synonyms: IL-13, NC30
    分子量
    150 kDa
    基因ID
    16163
    NCBI登录号
    NP_032381
    UniProt
    P20109
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
You are here:
客服