IL-13 抗体
Quick Overview for IL-13 抗体 (ABIN116389)
抗原
See all IL-13 (IL13) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Reacts with Murine Interleukin 13.
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纯化方法
- Affinity chromatography.
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免疫原
- Highly purified (>98%) recombinant mouse IL-13
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anti-Interleukin 13 (IL13) (AA 45-56) antibody
IL13 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-146) antibodyIL13 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-146) antibodyIL13 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2B5 unconjugated
anti-Interleukin 13 (IL13) (AA 118-146) antibodyIL13 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 25-131) antibodyIL13 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) (AA 30-125) antibodyIL13 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 大鼠 ELISA, IHC, FACS, IHC (p) 宿主: 小鼠 Monoclonal A130D 12G5 1E4 unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 7A7 unconjugated
anti-Interleukin 13 (IL13) antibodyIL13 适用: 人 WB, ELISA, IHC, Neut, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Neutralization. ELISA: (Indirect): To detect mIL-13 by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant mIL-13. (Sandwich): To detect mIL-13 by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purified
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限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
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- IL-13 (IL13) (Interleukin 13 (IL13))
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别名
- Interleukin-13 / IL13
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背景
- Human IL13 was originally identified by differential screening of an anti CD28 activated human peripheral blood mononuclear cell cDNA library as an induction specific novel cytokine. It was also isolated from cDNA libraries of human T cell clones using the murine IL13 (P600) cDNA as a probe. Human IL13, a pleiotropic cytokine, is produced by activated Th0, Th1 like, Th2 like, and CD8 T cells. The gene for human IL13 maps to chromosome 5 and is closely linked to the genes for IL3, IL4, IL5, and GMCSF. IL13 inhibits proinflammatory cytokine production and stimulates antibody production. It induces proliferation in the human pre myeloid cell line TF1. IL13 has multiple effects on the differentiation and functions of monocytes and macrophages. It suppresses cytotoxic functions and induces changes in the morphology of human monocytes and in the phenotype of human monocytes and B cells by upregulating MHC class II expression. IL13 will also decrease the production of nitric oxide by activated murine macrophages, leading to impaired parasiticidal activity. Human and mouse interleukin 13 share approximately 58 % amino acid sequence identity. Although human and mouse IL13 are equally active on human cells, human IL13 is much less active than mouse IL13 on mouse cells. Human IL13 and human IL4 also share approximately 30 % sequence homology and have similar biological functions.Synonyms: IL-13, NC30
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分子量
- 150 kDa
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基因ID
- 16163
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NCBI登录号
- NP_032381
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UniProt
- P20109
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
抗原
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