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CCL19 抗体 (Biotin)

This anti-CCL19 antibody is a 兔 多克隆 antibody detecting CCL19 in WB 和 EIA. Suitable for 人.
产品编号 ABIN116173
发货至: 中国

Quick Overview for CCL19 抗体 (Biotin) (ABIN116173)

抗原

See all CCL19 抗体
CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

适用

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宿主

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克隆类型

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多克隆

标记

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This CCL19 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 特异性

    Human Macrophage Inflammatory Protein-3 beta (MIP-3 beta).

    纯化方法

    Affinity chromatography.

    免疫原

    Highly pure (>98%) recombinant hMIP-3 beta (human MIP-3 beta).
  • 应用备注

    ELISA: To detect hMIP-3 beta by direct ELISA (using 100 l/well antibody solution) thisantibody can be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction withcompatible secondary reagents, allows the detection of at least 0.2 ng/well of recombinanthMIP-3 betaWestern Blot: To detect hMIP-3 beta by Western Blot analysis this antibody can be used ata concentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMIP-3 beta is 1.5 - 3.0 ng/lane, under eitherreducing or non-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.2 without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

    储存条件

    4 °C/-20 °C

    储存方法

    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原

    CCL19 (Chemokine (C-C Motif) Ligand 19 (CCL19))

    别名

    MIP3-beta / CCL19

    背景

    MIP3 chemokines are among many novel beta chemokines recently identified through bioinformatics in the Expressed Sequence Tag (EST) database. They are distantly related to other beta chemokines (20-30 % aa sequence homology). MIP3 chemokines are useful probes for studying the biology of inflammation and cell migration. Their expression is strongly up-regulated by inflammatory signals and down-regulated by the anti-inflammatory cytokine IL10. MIP3 beta is also known as ELC (EBI1-1 ligand chemokine) and is constitutively expressed in various lymphoid tissues (thymus, lymph nodes, appendix and spleen). MIP3 beta is a chemoattractant for cultured human lymphocytes, dendritic cells, human T lymphoblastoid CEM NKR2 and hemopoietic progenitor cells. It may be involved in G Protein activation in human NK cells. MIP3 beta is a unique functional ligand for CCR7. The MIP3 beta gene has been mapped to chormosome 9p13.Synonyms: Beta chemokine exodus-3, C-C motif chemokine 19, CCL-19, CK beta-11, EBI1-ligand chemokine, ELC, Exodus-3, MIP-3 beta, MIP3B, Macrophage inflammatory protein 3 beta, SCYA19, Small-inducible cytokine A19, Small-inducible cytokine A19

    基因ID

    6363

    NCBI登录号

    NP_006265

    UniProt

    Q99731

    途径

    Positive Regulation of Immune Effector Process
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