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IL-13 抗体 (Biotin)

IL13 适用: 人 WB, EIA 宿主: 兔 Polyclonal Biotin
产品编号 ABIN116105
发货至: 中国
  • 抗原 See all IL-13 (IL13) 抗体
    IL-13 (IL13) (Interleukin 13 (IL13))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This IL-13 antibody is conjugated to Biotin
    应用范围
    • 84
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    Reacts with Human IL-13.
    纯化方法
    Affinity chromatography.
    免疫原
    Highly pure (>98%) recombinant hIL-13 (human IL-13).
    Top Product
    Discover our top product IL13 Primary Antibody
  • 应用备注
    ELISA: To detect hIL-13 by direct ELISA (using 100 l/well antibody solution) this antibodycan be used at a concentration of 0.15 - 0.30 μg/mL. Used in conjunction with compatiblesecondary reagents, allows the detection of at least 0.2 ng/well of recombinant hIL-13. Western Blot: To detect hIL-13 by Western Blot analysis this antibody can be used at aconcentration of 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hIL-13 is 1.5 - 3.0 ng/lane, under either reducing ornon-reducing conditions.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile PBS containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    IL-13 (IL13) (Interleukin 13 (IL13))
    别名
    Interleukin-13 / IL13 (IL13 产品)
    别名
    IL13 antibody, IL-13 antibody, P600 antibody, Il-13 antibody, L13 antibody, interleukin 13 antibody, IL13 antibody, Il13 antibody
    背景
    Human IL13 was originally identified by differential screening of an anti CD28 activated human peripheral blood mononuclear cell cDNA library as an induction specific novel cytokine. It was also isolated from cDNA libraries of human T cell clones using the murine IL13 (P600) cDNA as a probe. Human IL13, a pleiotropic cytokine, is produced by activated Th0, Th1 like, Th2 like, and CD8 T cells. The gene for human IL13 maps to chromosome 5 and is closely linked to the genes for IL3, IL4, IL5, and GMCSF. IL13 inhibits proinflammatory cytokine production and stimulates antibody production. It induces proliferation in the human pre myeloid cell line TF1. IL13 has multiple effects on the differentiation and functions of monocytes and macrophages. It suppresses cytotoxic functions and induces changes in the morphology of human monocytes and in the phenotype of human monocytes and B cells by upregulating MHC class II expression. IL13 will also decrease the production of nitric oxide by activated murine macrophages, leading to impaired parasiticidal activity. Human and mouse interleukin 13 share approximately 58 % amino acid sequence identity. Although human and mouse IL13 are equally active on human cells, human IL13 is much less active than mouse IL13 on mouse cells. Human IL13 and human IL4 also share approximately 30 % sequence homology and have similar biological functions.Synonyms: IL-13, NC30
    基因ID
    3596
    NCBI登录号
    NP_002179
    UniProt
    P35225
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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