CCL3 抗体
Our Local Distributor
北京 101111
Quick Overview for CCL3 抗体 (ABIN115905)
抗原
See all CCL3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
纯化方法
- Affinity chromatography.
-
免疫原
- Highly pure (>98%) recombinant mMIP-1 alpha.
-
-
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) antibody
CCL3 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E7 unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 25-81) antibodyCCL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 59-87), (C-Term) antibodyCCL3 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21614 unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 24-92) antibodyCCL3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
-
-
应用备注
- Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mMIP-1 alpha (10 ng/mL), a concentration of 2.0-5.0 μg/mL of a previous lot of this antibody was required. ELISA: (Indirect): To detect hMIP-1α by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant hMIP-1α. (Sandwich): To detect hMIP-1α by sandwich ELISA (using 100 μL/well antibody solution) aconcentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with Biotinylated Anti-Murine MIP-1α (PP017B) as a detectionantibody, allows the detection of at least 0.2-0.4 ng/well of recombinant hMIP-1α. Western Blot: To detect mMIP-1α by Western Blot analysis this antibody can be used at a concentration of0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit
-
限制
- 仅限研究用
-
-
-
溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
-
缓冲液
- PBS, pH 7.2 without preservatives.
-
储存液
- Without preservative
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
-
-
- CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))
-
别名
- MIP1 alpha / CCL3
-
背景
- Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77 % and 70 % amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.Synonyms: C-C motif chemokine 3, CCL-3, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, LD78 alpha, MIP-1-alpha, MIP1A, Macrophage Inflammatory Protein 1 alpha, SCYA3, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein
-
基因ID
- 20302
-
NCBI登录号
- NP_035467
-
UniProt
- P10855
-
途径
- Cellular Response to Molecule of Bacterial Origin, Autophagy
抗原
-
