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IL-7 抗体

IL7 适用: 小鼠 WB, EIA, Func 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN115889
发货至: 中国
  • 抗原 See all IL-7 (IL7) 抗体
    IL-7 (IL7) (Interleukin 7 (IL7))
    适用
    • 47
    • 31
    • 25
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 63
    • 13
    • 9
    • 1
    • 1
    克隆类型
    • 66
    • 21
    多克隆
    标记
    • 46
    • 14
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL-7 antibody is un-conjugated
    应用范围
    • 69
    • 38
    • 19
    • 16
    • 13
    • 13
    • 7
    • 7
    • 5
    • 5
    • 5
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    Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
    特异性
    This antibody recognizes Mouse Interleukin-7 (IL-7). Other species not tested.
    纯化方法
    Affinity Chromatography immobilized Murine IL-7 matrix
    免疫原
    Highly pure (>98%) E.coli derived recombinant Mouse IL-7 (Cat.-No PA014)
    Top Product
    Discover our top product IL7 Primary Antibody
  • 应用备注
    Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity of mIL-7 (0.60 ng/mL),a concentration of 0.012 - 0.02 μg/mL of this antibody is required. ELISA: To detect mIL-7 by direct ELISA (using 100 l/well antibody solution) a concentration of atleast 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, inconjunction with compatible secondary reagents, allows the detection of 0.2-0.4 ng/wellof recombinant mIL-7. Western Blot: To detect mIL-7 by Western Blot analysis this antibody can be used at a concentration of0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limitfor recombinant mIL-7 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives.
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing. Centrifuge vial prior to opening!
    储存条件
    4 °C/-20 °C
    储存方法
    Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
  • 抗原
    IL-7 (IL7) (Interleukin 7 (IL7))
    别名
    Interleukin-7 / IL7 (IL7 产品)
    别名
    IL7 antibody, IL-7 antibody, A630026I06Rik antibody, Il-7 antibody, hlb368 antibody, interleukin 7 antibody, IL7 antibody, Il7 antibody
    背景
    Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL7 stimulates the proliferation of CD4+/CD8+ cells. The proliferative response of thymocytes to IL7 is not affected by antibodies to the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors. Mature T cells respond to IL7 and Con A, but not to IL7 alone. In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages. IL7 is expressed by adherent stromal cells from various tissues.Synonyms: IL-7
    基因ID
    16196
    NCBI登录号
    NP_032397
    UniProt
    P10168
    途径
    JAK/STAT Signaling
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