IL-7 抗体
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北京 101111
Quick Overview for IL-7 抗体 (ABIN115765)
抗原
See all IL-7 (IL7) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognises Human IL-7.
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Recombinant human IL-7.
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亚型
- IgG1
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anti-Interleukin 7 (IL7) (AA 1-177) antibody
IL7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) antibodyIL7 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) (AA 26-177) antibodyIL7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) (AA 26-177) antibodyIL7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) (AA 51-154) antibodyIL7 适用: 大鼠 WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) (AA 26-177) antibodyIL7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C12 unconjugated
anti-Interleukin 7 (IL7) antibodyIL7 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) (C-Term) antibodyIL7 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 7 (IL7) antibody (Biotin)IL7 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
anti-Interleukin 7 (IL7) antibody (Biotin)IL7 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
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Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofhIL-7 (0.5 ng/mL), a concentration of 0.05-0.08 μg/mL of this antibody is required. ELISA: In a Sandwich ELISA (assuming 100μL/well), a concentration of 2.0-4.0 μg/mL of thisantibody will detect at least 1000 pg/mL of recombinant Human IL-7 when used withBuiotin anti-Human IL-7 antibody (PP1029B1 or PP1029B2) as the detection antibody at aconcentration of approximately 0.5-1.0 μg/mL. Western Blot: To detect Hunman IL-7 by Western Blot analysis this antibody can be used ata concentration of 1.0-2.0 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant Human IL-7 is 2.0-4.0 ng/lane, under reducingconditions and 0.25-0.50 ng/lane, under non-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 1.0 mg/mL.
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缓冲液
- PBS without preservatives.
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- IL-7 (IL7) (Interleukin 7 (IL7))
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别名
- Interleukin-7 / IL7
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背景
- Interleukin 7 (IL7) is a lymphoid cell growth factor that affects pre-B, pro-B, and early T cells. IL7 was previously known as pre-B cell growth factor and lymphopoietin 1. IL7 supports the growth of early B cells from long-term lymphoid bone marrow cultures. It is mitogenic to thymocytes and enhances the response of cells to other stimuli such as polyhydroxyalkanoate (PHA) and concanavalin A (ConA). IL7 stimulates the proliferation of CD4+/CD8+ cells. The proliferative response of thymocytes to IL7 is not affected by antibodies to the T cell growth factors such as IL2, IL4 and IL6, suggesting that IL7 is capable of stimulating T cell proliferation through a pathway independent of the known T cell growth factors. Mature T cells respond to IL7 and Con A, but not to IL7 alone. In myeloid lineage cells, IL7 upregulates the production of pro-inflammatory cytokines and stimulates the tumoricidal activity of monocytes/macrophages. IL7 is expressed by adherent stromal cells from various tissues.Synonyms: IL-7
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基因ID
- 3574
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NCBI登录号
- NP_000871
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UniProt
- P13232
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途径
- JAK/STAT Signaling
抗原
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