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Endoglin 抗体 (AA 26-581)

Name: Endoglin 抗体 (AA 26-581)
SKU: ABIN115701
Availability: OutOfStock

This anti-Endoglin antibody is a 兔多克隆 antibody detecting Endoglin in WB, FACS, IHC (fro) 和 EIA. Suitable for 小鼠.

产品编号 ABIN115701

发货至: 中国

Quick Overview for Endoglin 抗体 (AA 26-581) (ABIN115701)

抗原

See all Endoglin (ENG) 抗体

Endoglin (ENG)

适用

小鼠

宿主

兔

克隆类型

多克隆

标记

This Endoglin antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Discover our top product ENG Primary Antibody

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AA 26-581

纯化方法

Antigen affinity chromatography

免疫原

Recombinant mouse soluble CD105/Endoglin. It consists of amino acid 26 (Glu) to 581 (Gly) and is fused to a C-terminal His-tag (6xHis).
anti-Endoglin (ENG) (AA 58-110) antibody
ENG 适用: 人, 小鼠, 大鼠, 犬 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 27-137) antibody
ENG 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 26-136) antibody
ENG 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 26-136) antibody
ENG 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG 适用: 人 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A9 unconjugated

anti-Endoglin (ENG) (AA 27-226) antibody
ENG 适用: 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) (AA 601-658) antibody
ENG 适用: 人, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Endoglin (ENG) antibody
ENG 适用: 人, 大鼠 WB, FACS, IP, MS 宿主: 小鼠 Monoclonal MEM-226 unconjugated

anti-Endoglin (ENG) antibody (APC)
ENG 适用: 人, 大鼠 FACS 宿主: 小鼠 Monoclonal MEM-226 APC

anti-Endoglin (ENG) (AA 370-430) antibody
ENG 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA (1 - 15 μg/mL). Western blot (1 - 2 μg/mL). Flow cytometry (3 - 20 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

限制

仅限研究用
溶解方式

Reconstitute in sterile water/PBS to a concentration of >0.5 mg/mL

缓冲液

Immunglobulin fraction in Phosphate buffered saline pH 7.4 without preservative and stabilizer

储存液

Without preservative

注意事项

Avoid repeated freeze-thaw cycles. Following reconstitution the antibody is stable for six weeks at 2-8°C.

储存条件

4 °C/-20 °C

储存方法

The lyophilized IgG is stable at 2-8 °C for one month and for one year from despatch when kept at -20 °C.

有效期

12 months
抗原

Endoglin (ENG)

别名

CD105 / Endoglin

背景

Endoglin, also known as CD105, is a Type I integral membrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated, cytoplasmic tail. Two splice variants of human endoglin, the S-endoglin and L-endoglin that differ in the length of their cytoplasmic tails have been identified. Endoglin is highly expressed on vascular endothelial cells, chondrocytes, and syncytiotrophoblasts of term placenta. It is also found on activated monocytes, bone marrow pro-erythroblasts, and leukemic cells of lymphoid and myeloid lineages. Human and mouse endoglin share approximately 70 % and 97 % amino acid sequence identity in their extracellular and intracellular domains, respectively. It has clearly been shown that CD105/Endoglin is required for angiogenesis and it plays a key role in heart development. Mutations in human endoglin or ALK-1 (another type I serine/threonine receptor) lead to the vascular disorder hereditary hemorrhagic telangiectasia (HHT). Mice heterozygous for endoglin have been developed as disease models for HHT. Endoglin has been shown to be a powerful marker of neovascularization. It is also useful as a functional marker that defines long-term repopulating hematopoietic stem cells.Synonyms: END, ENG, HHT1, ORW, ORW1

基因ID

10090

UniProt

Q63961