PROX1 抗体 (C-Term)
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Quick Overview for PROX1 抗体 (C-Term) (ABIN115694)
抗原
See all PROX1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects Prox-1 in the nucleus of lymphatic endothelial cells.
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交叉反应 (详细)
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Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse. -
纯化方法
- Protein A Chromatography
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免疫原
- Highly pure (>95%) recombinant Human, highly conserved C-terminal part of Prox1 (homeo domain and prospero domain) derived from E.coli.
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应用备注
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Western blot (1 - 5 μg/mL). Immunofluorescence (1: 750 - 1: 1000). Immunohistochemistry: the antibody works well with paraffin sections. A boiling step isrecommended when staining paraffin-embedded tissues.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- 5 mM PBS, pH 7.4 without stabilizer or preservative
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PROX1 (Prospero Homeobox 1 (PROX1))
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别名
- PROX-1
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背景
- Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1
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基因ID
- 5629
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NCBI登录号
- NP_002754
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UniProt
- Q92786
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途径
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
抗原
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