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LYVE1 抗体 (AA 24-226)

LYVE1 适用: 小鼠 WB, FACS, IF, IHC (fro), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN115690
发货至: 中国
  • 抗原 See all LYVE1 抗体
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    抗原表位
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-226
    适用
    • 76
    • 56
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 83
    • 6
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 84
    • 12
    多克隆
    标记
    • 52
    • 11
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LYVE1 antibody is un-conjugated
    应用范围
    • 84
    • 40
    • 38
    • 20
    • 18
    • 9
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detetcs Lyve-1.
    交叉反应 (详细)
    Species reactivity (tested):Mouse. This antibody is not reactive with Human LYVE-1.
    纯化方法
    Protein G Chromatography (+ his tag depletetion)
    免疫原
    Highly pure recombinant Mouse soluble LYVE-1 produced in insect cells. This recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
    Top Product
    Discover our top product LYVE1 Primary Antibody
  • 应用备注
    ELISA (1-15 μg/mL). Western blot (1-2 μg/mL). FACS analysis (3-20 μg/mL). Immunohistochemistry on Frozen Sections (1-5 μg/mL). For formalin-fixed, paraffin-embedded sections use the immunogen affinity purifiedantibody ABIN115689.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water/PBS to a concentration of > 0.5 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives or stabilizers
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized IgG is stable at 2-8 °C for one month and at -20 °C for longer. When reconstituted the antibody is stable for at least six weeks at 2-8 °C. For longer store in aliquots at -20 °C.
  • Rivera-Pagán, Rivera-Aponte, Melnik-Martínez, Zayas-Santiago, Kucheryavykh, Martins, Cubano, Skatchkov, Eaton: "Up-regulation of TREK-2 potassium channels in cultured astrocytes requires de novo protein synthesis: relevance to localization of TREK-2 channels in astrocytes after transient cerebral ischemia." in: PLoS ONE, Vol. 10, Issue 4, pp. e0125195, (2016) (PubMed).

    Rangel-Moreno, de la Luz Garcia-Hernandez, Ramos-Payan, Biear, Hernady, Sangster, Randall, Johnston, Finkelstein, Williams: "Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function." in: Radiation research, Vol. 184, Issue 4, pp. 352-66, (2015) (PubMed).

    Tamhane, Arampatzidou, Gerganova, Tacke, Illukkumbura, Dauth, Schaschke, Peters, Reinheckel, Brix: "The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length." in: Biological chemistry, Vol. 395, Issue 10, pp. 1201-19, (2015) (PubMed).

    Göttle, Sabo, Heinen, Venables, Torres, Tzekova, Parras, Kremer, Hartung, Cate, Küry: "Oligodendroglial maturation is dependent on intracellular protein shuttling." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 906-19, (2015) (PubMed).

    Schoenherr, Saul, Whiteaker, Yan, Whiteley, Paulovich: "Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 2, pp. 382-98, (2015) (PubMed).

    Rodriguez-Perez, Borrajo, Valenzuela, Lanciego, Labandeira-Garcia: "Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats." in: Neurobiology of aging, Vol. 36, Issue 2, pp. 1194-208, (2015) (PubMed).

    Lu, Gui, Yao, Yan, Martens, Aschenbach, Shen: "Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 308, Issue 4, pp. R283-93, (2015) (PubMed).

    Hedner, Gaber, Korkocic, Nodin, Uhlén, Kuteeva, Johannesson, Jirström, Eberhard: "SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma." in: Virchows Archiv : an international journal of pathology, Vol. 465, Issue 6, pp. 649-59, (2015) (PubMed).

    Banerjee, Bandyopadhyay: "Cytosolic dynamics of annexin A6 trigger feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes." in: The Journal of biological chemistry, Vol. 289, Issue 9, pp. 5371-85, (2014) (PubMed).

    Walpole, Farrell, McGrane, Stewart: "Expression and localization of a UT-B urea transporter in the human bladder." in: American journal of physiology. Renal physiology, Vol. 307, Issue 9, pp. F1088-94, (2014) (PubMed).

    Forsström, Axnäs, Stengele, Bühler, Albert, Richmond, Hu, Nilsson, Hudson, Rockberg, Uhlen: "Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 6, pp. 1585-97, (2014) (PubMed).

    Boman, Larsson, Segersten, Kuteeva, Johannesson, Nodin, Eberhard, Uhlén, Malmström, Jirström: "Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer." in: British journal of cancer, Vol. 108, Issue 11, pp. 2321-8, (2013) (PubMed).

    Braunschweig, Krakowiak, Duncanson, Boyce, Hansen, Ashwood, Hertz-Picciotto, Pessah, Van de Water: "Autism-specific maternal autoantibodies recognize critical proteins in developing brain." in: Translational psychiatry, Vol. 3, pp. e277, (2013) (PubMed).

    Ye, Gao, Tian, Yearsley, Lange, Robertson, Barsky: "Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7." in: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 713-26, (2012) (PubMed).

    Hayano, Kurosaka, Yanagita, Kalus, Milz, Ishihara, Islam, Kawanabe, Saito, Kamioka, Adachi, Dierks, Yamashiro: "Roles of heparan sulfate sulfation in dentinogenesis." in: The Journal of biological chemistry, Vol. 287, Issue 15, pp. 12217-29, (2012) (PubMed).

    Heishi, Hosaka, Suzuki, Miyashita, Oike, Takahashi, Nakamura, Arioka, Mitsuda, Takakura, Hojo, Matsumoto, Yamauchi, Ohta, Sonoda, Sato: "Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1950-8, (2010) (PubMed).

    Conrad, Niess, Huss, Huber, von Luettichau, Nelson, Ott, Jauch, Bruns: "Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo." in: Circulation, Vol. 119, Issue 2, pp. 281-9, (2009) (PubMed).

    Shaham, Smith, Robinson, Taketo, Lang, Ashery-Padan: "Pax6 is essential for lens fiber cell differentiation." in: Development (Cambridge, England), Vol. 136, Issue 15, pp. 2567-78, (2009) (PubMed).

    Veres, Shevchenko, Krasteva, Spies, Prenzler, Rochlitzer, Tschernig, Krug, Kummer, Braun: "Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation." in: The American journal of pathology, Vol. 174, Issue 3, pp. 808-17, (2009) (PubMed).

  • 抗原
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    别名
    LYVE-1 (LYVE1 产品)
    别名
    LYVE1 antibody, XLKD1 antibody, CRSBP-1 antibody, HAR antibody, LYVE-1 antibody, 1200012G08Rik antibody, Crsbp-1 antibody, Lyve-1 antibody, Xlkd1 antibody, lymphatic vessel endothelial hyaluronic receptor 1a antibody, lymphatic vessel endothelial hyaluronan receptor 1 antibody, lyve1a antibody, LYVE1 antibody, Lyve1 antibody
    背景
    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212- esidue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE- molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymphspecific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
    基因ID
    114332
    NCBI登录号
    NP_444477
    UniProt
    Q8BHC0
    途径
    Glycosaminoglycan Metabolic Process
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