LYVE1 抗体 (AA 24-226)
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北京 101111
Quick Overview for LYVE1 抗体 (AA 24-226) (ABIN115690)
抗原
See all LYVE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-226
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特异性
- This antibody detetcs Lyve-1.
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交叉反应 （详细）
- Species reactivity (tested):Mouse. This antibody is not reactive with Human LYVE-1.
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纯化方法
- Protein G Chromatography (+ his tag depletetion)
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免疫原
- Highly pure recombinant Mouse soluble LYVE-1 produced in insect cells. This recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
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anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 231-318) antibody
LYVE1 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 46-77), (N-Term) antibodyLYVE1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB2930 unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) antibodyLYVE1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 人 WB, FACS, ICC 宿主: 兔 Monoclonal 24GB340 unconjugated Recombinant Antibody
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 24-228) antibodyLYVE1 适用: 小鼠, 大鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 20-238) antibodyLYVE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) (AA 25-235) antibodyLYVE1 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal 4G1 unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1) antibodyLYVE1 适用: 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA (1-15 μg/mL). Western blot (1-2 μg/mL). FACS analysis (3-20 μg/mL). Immunohistochemistry on Frozen Sections (1-5 μg/mL). For formalin-fixed, paraffin-embedded sections use the immunogen affinity purifiedantibody ABIN115689.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water/PBS to a concentration of > 0.5 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives or stabilizers
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- The lyophilized IgG is stable at 2-8 °C for one month and at -20 °C for longer. When reconstituted the antibody is stable for at least six weeks at 2-8 °C. For longer store in aliquots at -20 °C.
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: "Up-regulation of TREK-2 potassium channels in cultured astrocytes requires de novo protein synthesis: relevance to localization of TREK-2 channels in astrocytes after transient cerebral ischemia." in: PLoS ONE, Vol. 10, Issue 4, pp. e0125195, (2016) (PubMed).
: "Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function." in: Radiation research, Vol. 184, Issue 4, pp. 352-66, (2015) (PubMed).
: "The activity and localization patterns of cathepsins B and X in cells of the mouse gastrointestinal tract differ along its length." in: Biological chemistry, Vol. 395, Issue 10, pp. 1201-19, (2015) (PubMed).
: "Oligodendroglial maturation is dependent on intracellular protein shuttling." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 906-19, (2015) (PubMed).
: "Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 2, pp. 382-98, (2015) (PubMed).
: "Critical period for dopaminergic neuroprotection by hormonal replacement in menopausal rats." in: Neurobiology of aging, Vol. 36, Issue 2, pp. 1194-208, (2015) (PubMed).
: "Short-chain fatty acids and acidic pH upregulate UT-B, GPR41, and GPR4 in rumen epithelial cells of goats." in: American journal of physiology. Regulatory, integrative and comparative physiology, Vol. 308, Issue 4, pp. R283-93, (2015) (PubMed).
: "SATB1 is an independent prognostic factor in radically resected upper gastrointestinal tract adenocarcinoma." in: Virchows Archiv : an international journal of pathology, Vol. 465, Issue 6, pp. 649-59, (2015) (PubMed).
: "Cytosolic dynamics of annexin A6 trigger feedback regulation of hypertrophy via atrial natriuretic peptide in cardiomyocytes." in: The Journal of biological chemistry, Vol. 289, Issue 9, pp. 5371-85, (2014) (PubMed).
: "Expression and localization of a UT-B urea transporter in the human bladder." in: American journal of physiology. Renal physiology, Vol. 307, Issue 9, pp. F1088-94, (2014) (PubMed).
: "Proteome-wide epitope mapping of antibodies using ultra-dense peptide arrays." in: Molecular & cellular proteomics : MCP, Vol. 13, Issue 6, pp. 1585-97, (2014) (PubMed).
: "Membranous expression of podocalyxin-like protein is an independent factor of poor prognosis in urothelial bladder cancer." in: British journal of cancer, Vol. 108, Issue 11, pp. 2321-8, (2013) (PubMed).
: "Autism-specific maternal autoantibodies recognize critical proteins in developing brain." in: Translational psychiatry, Vol. 3, pp. e277, (2013) (PubMed).
: "Early to intermediate steps of tumor embolic formation involve specific proteolytic processing of E-cadherin regulated by Rab7." in: Molecular cancer research : MCR, Vol. 10, Issue 6, pp. 713-26, (2012) (PubMed).
: "Roles of heparan sulfate sulfation in dentinogenesis." in: The Journal of biological chemistry, Vol. 287, Issue 15, pp. 12217-29, (2012) (PubMed).
: "Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1950-8, (2010) (PubMed).
: "Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo." in: Circulation, Vol. 119, Issue 2, pp. 281-9, (2009) (PubMed).
: "Pax6 is essential for lens fiber cell differentiation." in: Development (Cambridge, England), Vol. 136, Issue 15, pp. 2567-78, (2009) (PubMed).
: "Dendritic cell-nerve clusters are sites of T cell proliferation in allergic airway inflammation." in: The American journal of pathology, Vol. 174, Issue 3, pp. 808-17, (2009) (PubMed).
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: "Up-regulation of TREK-2 potassium channels in cultured astrocytes requires de novo protein synthesis: relevance to localization of TREK-2 channels in astrocytes after transient cerebral ischemia." in: PLoS ONE, Vol. 10, Issue 4, pp. e0125195, (2016) (PubMed).
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- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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别名
- LYVE-1
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背景
- LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212- esidue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE- molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymphspecific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
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基因ID
- 114332
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NCBI登录号
- NP_444477
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UniProt
- Q8BHC0
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途径
- Glycosaminoglycan Metabolic Process
抗原
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