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LYVE1 抗体 (AA 24-228)

LYVE1 适用: 小鼠 WB, FACS, IF, IHC (fro), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN115688
发货至: 中国
  • 抗原 See all LYVE1 抗体
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    抗原表位
    • 13
    • 12
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-228
    适用
    • 76
    • 56
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 83
    • 6
    • 4
    • 1
    • 1
    • 1
    克隆类型
    • 84
    • 12
    多克隆
    标记
    • 52
    • 11
    • 7
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LYVE1 antibody is un-conjugated
    应用范围
    • 84
    • 40
    • 38
    • 20
    • 18
    • 9
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detetcs Lyve-1.
    交叉反应 (详细)
    Species reactivity (tested):Mouse. This antibody is not reactive with Human LYVE-1.
    纯化方法
    Protein G Chromatography (+ his tag depletetion)
    免疫原
    Highly pure recombinant Mouse soluble LYVE-1 produced in insect cells. This recombinant soluble LYVE-1 consists of amino acid 24 (Ala) to 228 (Gly) and is fused to a C-terminal His-tag (6xHis).
    Top Product
    Discover our top product LYVE1 Primary Antibody
  • 应用备注
    ELISA (1-15 μg/mL). Western blot (1-2 μg/mL). FACS analysis (3-20 μg/mL). Immunohistochemistry on Frozen Sections (1-5 μg/mL). For formalin-fixed, paraffin-embedded sections use the immunogen affinity purifiedantibody ABIN115689.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water/PBS to a concentration of > 0.5 mg/mL.
    缓冲液
    PBS, pH 7.2 without preservatives or stabilizers
    储存液
    Without preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized IgG is stable at 2-8 °C for one month and at -20 °C for longer. When reconstituted the antibody is stable for at least six weeks at 2-8 °C. For longer store in aliquots at -20 °C.
  • Rangel-Moreno, de la Luz Garcia-Hernandez, Ramos-Payan, Biear, Hernady, Sangster, Randall, Johnston, Finkelstein, Williams: "Long-Lasting Impact of Neonatal Exposure to Total Body Gamma Radiation on Secondary Lymphoid Organ Structure and Function." in: Radiation research, Vol. 184, Issue 4, pp. 352-66, (2015) (PubMed).

    Heishi, Hosaka, Suzuki, Miyashita, Oike, Takahashi, Nakamura, Arioka, Mitsuda, Takakura, Hojo, Matsumoto, Yamauchi, Ohta, Sonoda, Sato: "Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1950-8, (2010) (PubMed).

    Conrad, Niess, Huss, Huber, von Luettichau, Nelson, Ott, Jauch, Bruns: "Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo." in: Circulation, Vol. 119, Issue 2, pp. 281-9, (2009) (PubMed).

  • 抗原
    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
    别名
    LYVE-1 (LYVE1 产品)
    别名
    LYVE1 antibody, XLKD1 antibody, CRSBP-1 antibody, HAR antibody, LYVE-1 antibody, 1200012G08Rik antibody, Crsbp-1 antibody, Lyve-1 antibody, Xlkd1 antibody, lymphatic vessel endothelial hyaluronic receptor 1a antibody, lymphatic vessel endothelial hyaluronan receptor 1 antibody, lyve1a antibody, LYVE1 antibody, Lyve1 antibody
    背景
    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosaminoglycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212- esidue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE- molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymphspecific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
    基因ID
    114332
    NCBI登录号
    NP_444477
    UniProt
    Q8BHC0
    途径
    Glycosaminoglycan Metabolic Process
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