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FGF2 抗体

FGF2 适用: 人 WB, Func 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN115676
发货至: 中国
  • 抗原 See all FGF2 抗体
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
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    克隆类型
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    多克隆
    标记
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    This FGF2 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Functional Studies (Func)
    特异性
    The antibody will detect FGF-2 (basic).
    纯化方法
    Protein A affinity chromatography
    免疫原
    Highly pure (> 98%) recombinant human FGF-2 (basic)
    Top Product
    Discover our top product FGF2 Primary Antibody
  • 应用备注
    Neutralization: To yield one-half maximal inhibition (ND50) of the biological activity of human FGF-2 basic(5 ng/mL) on HUVEC cells, a concentration of about 3.5 μg/mL of this antibody is required. Western Blot: To detect human FGF-2 basic by Western blot this antibody can be used at a concentrationof 0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant human FGF-2 (basic) is 1.5 -3.0 ng/lane, under either reducing ornon-reducing conditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 溶解方式
    Restore in sterile water to a concentration of > / = 0.2 mg/mL.
    缓冲液
    PBS, pH 7.4, without stabilizer or preservative
    储存液
    Without preservative
    储存条件
    4 °C/-20 °C
    储存方法
    The lyophilized antibody is stable at room temperature for one month and for one year from despatch when kept at -20 °C. When reconstituted in sterile water to a concentration of > / = 0.2 mg/ml the antibody is stable for six weeks at 2-8 °C.
    有效期
    12 months
  • 抗原
    FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
    别名
    FGF Basic / FGF2 (FGF2 产品)
    别名
    BFGF antibody, FGF-2 antibody, FGFB antibody, HBGF-2 antibody, Fgf-2 antibody, Fgfb antibody, bFGF antibody, fibroblast growth factor 2 antibody, fibroblast growth factor 2 (basic) antibody, FGF2 antibody, Fgf2 antibody, fgf2 antibody
    背景
    FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.Synonyms: BFGF, FGFB, Fibroblast growth factor 2 (basic), HBGF-2, HBGF2, Heparin-binding growth factor 2
    基因ID
    2247
    NCBI登录号
    NP_001997
    UniProt
    P09038
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
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