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LYVE1 抗体 (AA 24-231)

This 兔 多克隆 anti-LYVE1 antibody specifically detects LYVE1 in WB, FACS, IHC (p), EIA 和 IHC (fro). The antibody is reactive with 人 samples.
产品编号 ABIN115663
发货至: 中国
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Quick Overview for LYVE1 抗体 (AA 24-231) (ABIN115663)

抗原

See all LYVE1 抗体
LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

适用

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宿主

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克隆类型

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多克隆

标记

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This LYVE1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 24-231

    特异性

    This antibody will detect LYVE-1 on the surface of lymphatic endothelial cells by Immunohistochemistry. It detects a 70 kDa LYVE-1 band in Western blotting. This antibody is not reactive with Mouse LYVE-1.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Antigen Affinity Chromatography

    免疫原

    Highly pure recombinant Human soluble LYVE-1 produced in insect cells. It consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).
  • 应用备注

    Immunohistochemistry on Frozen and Paraffin Embedded Sections (1-5 μg/mL). Heat mediated antigen retrieval is recommended when staining paraffin embeddedsections. Western blot (1-2 μg/mL). ELISA (1-15 μg/mL). Flow Cytometry (3-20 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of 0.1-1.0 mg/mL

    缓冲液

    5 mM PBS, pH 7.2 without preservatives or stabilizers

    储存液

    Without preservative

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C. Protect from Light!
  • 抗原

    LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))

    别名

    LYVE-1

    背景

    LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosamino-glycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1

    基因ID

    10894

    NCBI登录号

    NP_006682

    UniProt

    Q9Y5Y7

    途径

    Glycosaminoglycan Metabolic Process
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