LYVE1 抗体 (AA 24-232)
Quick Overview for LYVE1 抗体 (AA 24-232) (ABIN115662)
抗原
See all LYVE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 24-232
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特异性
- The antibody recognizes LYVE-1.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A Chromatography (+ his tag depleted)
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免疫原
- Recombinant Human soluble LYVE-1 (24-232) produced in insect cells. Remarks: The recombinant soluble LYVE-1 consists of amino acid 24 (Ser) to 232 (Gly) and is fused to a C-terminal His-tag (6xHis).
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应用备注
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ELISA (1-15 μg/mL). Western blot (1-2 μg/mL). FACS analysis (3-20 μg/mL). Immunohistochemistry on Frozen Sections (6-30 μg/mL). Please Note: For use on Paraffin Embedded Sections the affinity-purified antibody(ABIN115663) is recommended.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of > 0.5 mg/mL.
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缓冲液
- PBS, pH 7.4 without preservatives or stabilizers
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- The lyophilized IgG is stable at 2-8 °C for one month or at -20 °C for one year from despatch. When reconstituted the antibody is stable for six weeks at 2-8 °C and at -20 °C for longer. Aliquot to
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有效期
- 12 months
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: "Tricyclic indole and dihydroindole derivatives as new inhibitors of soluble guanylate cyclase." in: Bioorganic & medicinal chemistry letters, Vol. 19, Issue 16, pp. 4810-3, (2009) (PubMed).
: "Distinctive localization and opposed roles of vasohibin-1 and vasohibin-2 in the regulation of angiogenesis." in: Blood, Vol. 113, Issue 19, pp. 4810-8, (2009) (PubMed).
: "First year changes of myocardial lymphatic endothelial markers in heart transplant recipients." in: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 29, Issue 5, pp. 767-71, (2006) (PubMed).
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: "Tricyclic indole and dihydroindole derivatives as new inhibitors of soluble guanylate cyclase." in: Bioorganic & medicinal chemistry letters, Vol. 19, Issue 16, pp. 4810-3, (2009) (PubMed).
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- LYVE1 (Lymphatic Vessel Endothelial Hyaluronan Receptor 1 (LYVE1))
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别名
- LYVE-1
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背景
- LYVE-1 has been identified as a major receptor for HA (extracellular matrix glycosamino-glycan hyaluronan) on the lymph vessel wall. The deduced amino acid sequence of LYVE-1 predicts a 322-residue type I integral membrane polypeptide 41 % similar to the CD44 HA receptor with a 212-residue extracellular domain containing a single Link module the prototypic HA binding domain of the Link protein superfamily. Like CD44, the LYVE-1 Molecule binds both soluble and immobilized HA. However, unlike CD44, the LYVE-1 Molecule colocalizes with HA on the luminal face of the lymph vessel wall and is completely absent from blood vessels. Hence, LYVE-1 is the first lymph-specific HA receptor to be characterized and is a uniquely powerful marker for lymph vessels themselves.Synonyms: CRSBP-1, CRSBP1, Cell surface retention sequence-binding protein 1, Extracellular link domain-containing protein 1, HAR, Hyaluronic acid receptor, LYVE1, Lymphatic vessel endothelial hyaluronic acid receptor 1, XLKD1
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基因ID
- 10894
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NCBI登录号
- NP_006682
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UniProt
- Q9Y5Y7
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途径
- Glycosaminoglycan Metabolic Process
抗原
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