ELISA. Western Blot. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
限制
仅限研究用
溶解方式
Restore with 0.1 mL of deionized water
浓度
1.0 mg/mL
缓冲液
0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE
储存液
Azide free
注意事项
Avoid repeated freezing and thawing.
储存条件
-20 °C
储存方法
Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.
有效期
6 months
抗原
CST3
(Cystatin C (CST3))
别名
Cystatin-C
背景
Cystatin C is a non-glycosilated basic single-chain protein consisting of 120 amino acids with a molecular weight of 13.36 kDa and is characterized by two disulfide bonds in the carboxy-terminal region. It belongs to the cystatins superfamilly which inactivates lysosomal cysteine proteinases, e.g. cathepsin B, H,.K, L and S. Imbalance between Cystatin C and cysteine proteinases is associated with inflammation, renal failure, cancer, Alzheimers disease, multiple sclerosis and hereditary Cystatin C amyloid angiopathy. Its increased level has been found in patients with autoimune diseases, with colorectal tumors and in patients on dyalisis. Serum Cystatin C seems to be better marker of glomerular filtration rate than creatinine. On the other hand, low concentration of Cystatin C presents a risk factor for secondary cardiovascular events.Synonyms: CST3, Cystatin C, Cystatin-3, Gamma-trace, Neuroendocrine basic polypeptide, Post-gamma-globulin