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GZMB 抗体 (N-Term)

GZMB 适用: 人, 小鼠, 大鼠 IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN115413
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    抗原表位
    • 18
    • 16
    • 13
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 118
    • 49
    • 24
    • 10
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 78
    • 43
    • 1
    克隆类型
    • 76
    • 46
    多克隆
    标记
    • 76
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is un-conjugated
    应用范围
    • 71
    • 42
    • 37
    • 37
    • 17
    • 17
    • 17
    • 14
    • 13
    • 9
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody reacts with a 32 kDa protein.
    Cellular Localization: Cytoplasmic
    纯化方法
    Purified
    免疫原
    A synthetic peptide from the N-terminus of human Granzyme B.
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    Immunohistochemistry on Paraffin Embedded Tissues: Use 1/50-1100 dilution in an ABC method (30 minutes at room temperature)Recommended Positive Control: Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    10 mM Citrate Buffer, pH 6.0 containing Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    GZMB (Granzyme B (GZMB))
    Abstract
    GZMB 产品
    别名
    CCPI antibody, CGL-1 antibody, CGL1 antibody, CSP-B antibody, CSPB antibody, CTLA1 antibody, CTSGL1 antibody, HLP antibody, SECT antibody, granzyme B antibody, GZMB antibody
    背景
    Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzymes B is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTLs or NK cells.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
    基因ID
    3002
    NCBI登录号
    NP_004122
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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