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GZMB 抗体 (N-Term)

The 兔 多克隆 anti-GZMB antibody (ABIN115413) specifically detects GZMB in IHC (p) 和 IHC (fro). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN115413
发货至: 中国
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Quick Overview for GZMB 抗体 (N-Term) (ABIN115413)

抗原

See all GZMB 抗体
GZMB (Granzyme B (GZMB))

适用

  • 175
  • 50
  • 25
  • 12
  • 4
  • 4
  • 3
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 100
  • 81
  • 4

克隆类型

  • 102
  • 83
多克隆

标记

  • 92
  • 16
  • 11
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GZMB antibody is un-conjugated

应用范围

  • 87
  • 76
  • 44
  • 43
  • 29
  • 29
  • 18
  • 18
  • 18
  • 14
  • 13
  • 10
  • 6
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 31
    • 17
    • 16
    • 12
    • 11
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody reacts with a 32 kDa protein.
    Cellular Localization: Cytoplasmic

    纯化方法

    Purified

    免疫原

    A synthetic peptide from the N-terminus of human Granzyme B.
  • 应用备注

    Immunohistochemistry on Paraffin Embedded Tissues: Use 1/50-1100 dilution in an ABC method (30 minutes at room temperature)Recommended Positive Control: Tonsil.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM Citrate Buffer, pH 6.0 containing Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GZMB (Granzyme B (GZMB))

    背景

    Granzymes are neutral serine proteases, which are stored in specialized lytic granules of cytotoxic T lymphocytes (CTLs) and in natural killer (NK) cells. A number of granzymes (A to G) have been isolated and cloned. Human granzymes B is involved in target cell apoptosis during lymphocyte-mediated cytotoxicity. This antibody is useful in the localization of granzyme B containing lytic granules and for the characterization of activated CTLs or NK cells.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E

    基因ID

    3002

    NCBI登录号

    NP_004122

    UniProt

    P10144

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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