KIT 抗体 (C-Term)
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Quick Overview for KIT 抗体 (C-Term) (ABIN115378)
抗原
See all KIT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
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This antibody reacts with a 145 kDa protein. This antibody can be used in the identification of gastrointestinal stromal tumors.
Cellular Localization: Cell membrane, cytoplasm. -
纯化方法
- Purified
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免疫原
- A synthetic peptide from c-terminus of Human CD117/c-kit protein.
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应用备注
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Immunohistochemistry on Paraffin Embedded Sections: Use 1/50-1/100 diluted antibody inan ABC method (30 minutes at room temperature). Recommended Positive Control: Tonsil.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- KIT (Mast/stem Cell Growth Factor Receptor (KIT))
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别名
- CD117 / C-Kit
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背景
- C-kits is expressed in many tissues and cells. c-kits is involved in the development of several lineages of stem cells, such as germ cells, neural crest derived melanocytes and hematopoietic precursor cells. This antibody can be used in the identification of gastrointestinal stromal tumors.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR
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基因ID
- 3815
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NCBI登录号
- NP_000213
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UniProt
- P10721
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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