ErbB2/Her2 抗体
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北京 101111
Quick Overview for ErbB2/Her2 抗体 (ABIN115291)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
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This antibody reacts with the c-erbB-2 oncoprotein, a 190 kDa protein.
Cellular Localization: Cell membrane -
纯化方法
- Purified
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免疫原
- Keyhole limpet hemocyanin conjugated synthetic human peptide c-erbB-2 oncoprotein.
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应用备注
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Immunohistochemistry on paraffin embedded sections: diluted of 1: 25-1: 50 in an ABC method (30 minutes at room temperature)Although not required, high temperature treatment may enhance the immunostaining inoverfixed tissues. Recommended Positive Control: Breast carcinoma
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- containing azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
- CD340 / ERBB2 / HER2
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背景
- The proto-oncogene for c-erbB-2 is located on the human chromosome 17, band 21. It has structural similarities to EGFR. Several studies have indicated that c-erbB-2 may be a good indicator of the prognosis of human carcinomas in the breast, ovary, uterus and gastrointestinal tract.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2
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基因ID
- 2064
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NCBI登录号
- NP_001005862
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UniProt
- P04626
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
抗原
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