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FLT4 抗体 (Extracellular Domain) (Biotin)

There is 1 publication for this product available. The 小鼠 单克隆 anti-FLT4 antibody is suitable to detect FLT4 in samples from 人. It has been validated for WB 和 EIA.
产品编号 ABIN115160
发货至: 中国
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Quick Overview for FLT4 抗体 (Extracellular Domain) (Biotin) (ABIN115160)

抗原

See all FLT4 抗体
FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This FLT4 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)

克隆位点

3C3
  • 抗原表位

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    Extracellular Domain

    特异性

    Detects Human VEGFR-3/FLT-4.

    纯化方法

    Affinity Chromatography on Protein G .

    免疫原

    Purified recombinant human Vascular Endothelial Growth Factor Receptor 3 (rh VEGFR-3/FLT-4) extracellular domain.

    亚型

    IgG1
  • 应用备注

    ELISA: 0.5-1.5 μg/mL in direct ELISA, allows detection of 0.25-0.5 ng/well. Western blot: 0.5-1 μg/mL, detection limit is approximately 5 ng/lane under reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of > 0.5 mg/mL.

    缓冲液

    0.1 M Tris-Cl, 0.1 M NaCl, pH 7.4 containing BSA (50x) as stabilizer and 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized IgG is stable at 2-8 °C for one month and for one year from despatch when kept at -20 °C. When reconstituted in sterile water to a concentration of > 0.5 mg/ml the antibody is stable for six weeks at 2-8 °C or at -20 °C for longer. Aliquot to

    有效期

    12 months
  • Davids, Davids, Charlton, Ng, Chong, Laubscher, Dar, Hodge, Soong, Goh: "Response to a novel multitargeted tyrosine kinase inhibitor pazopanib in metastatic Merkel cell carcinoma." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 27, Issue 26, pp. e97-100, (2009) (PubMed).

  • 抗原

    FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))

    别名

    VEGFR-3 / Flt-4

    背景

    VEGFR-3/FLT-4, belongs to the class III subfamily of receptor tyrosine kinases. VEGFR-3/FLT-4 mediates the angiogenic activity of VEGF-C and VEGF-D on lymphatic endothelial cells.Synonyms: FLT4, Tyrosine-protein kinase receptor FLT4, VEGF Receptor 3, VEGFR3, Vascular endothelial growth factor receptor 3

    基因ID

    2324

    NCBI登录号

    NP_002011

    UniProt

    P35916

    途径

    RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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