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TEK 抗体 (Extracellular Domain)

This anti-TEK antibody is a 小鼠 单克隆 antibody detecting TEK in WB, FACS, IHC (fro) 和 EIA. Suitable for 人.
产品编号 ABIN115159
发货至: 中国

Quick Overview for TEK 抗体 (Extracellular Domain) (ABIN115159)

抗原

See all TEK 抗体
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TEK antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

克隆位点

Cl-16
  • 抗原表位

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    Extracellular Domain

    特异性

    The monoclonal antibody will detect native Human TIE-2/tek in ELISA experiments and on the surface of different cell types.

    纯化方法

    Protein G Affinity Chromatoghraphy

    免疫原

    Recombinant Human soluble extracellular TIE-2 protein

    亚型

    IgG1
  • 应用备注

    ELISA: 1-15 μg/mL. Western blotting: 1-2 μg/mL. Flow cytometry and cell sorting (FACS): 2-5 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    缓冲液

    PBS, pH 7.4, without preservatives

    储存液

    Without preservative

    注意事项

    Avoid repeated freeze-thaw cycles!

    储存条件

    4 °C/-20 °C

    储存方法

    The lyophilized antibody, thought stable at room temperature, is best stored desiccated below 0 °C. Reconstituted anti-TIE-2/tek is stable at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    CD202b / TEK

    背景

    TIE2 (tyrosine kinase with Ig and EGF homology domains 2) is expressed almost exclusively in endothelial cells in mice, rats and humans. This receptor possesses a unique extracellular domain containing two immunoglobulin like loops separated by three epidermal growth factor like repeats that are connected to three fibronectin type III like repeats. The ligand for the receptor is Angiopoietin 1. Defects in TIE2 are associated with inherited venous malformations, the TIE2 signaling pathway appears to be critical for endothelial cell smooth muscle cell communication in venous morphogenesis.Synonyms: Angiopoietin-1 receptor, TIE-2, TIE2, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, p140 TEK

    基因ID

    7010

    NCBI登录号

    NP_000450

    UniProt

    Q02763

    途径

    RTK signaling, Growth Factor Binding
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