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ERCC1 抗体

ERCC1 适用: 人 WB, IHC (p), IP 宿主: 小鼠 Monoclonal 8F1 unconjugated
产品编号 ABIN115126
发货至: 中国
  • 抗原 See all ERCC1 抗体
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    适用
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    宿主
    • 55
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    小鼠
    克隆类型
    • 56
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    单克隆
    标记
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    This ERCC1 antibody is un-conjugated
    应用范围
    • 73
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    特异性
    This antibody reacts with a 33-36 kDa protein known as ERCC1 polypeptide. Cellular localization: Nuclear. Cross reacts with Rat.
    纯化方法
    Protein A Chromatography.
    免疫原
    BALB/C mice were injected with full length recombinant human ERCC1 protein.
    克隆位点
    8F1
    亚型
    IgG2b
    Top Product
    Discover our top product ERCC1 Primary Antibody
  • 应用备注
    Immunoprecipitation. Immunohistochemistry on Paraffin Embedded Sections: 1/100-1/200 in an ABC method. Formalin fixed paraffin embedded tissue sections require high temperature antigenunmasking with 10 mM citrate buffer, pH 6.0 prior to Immunostaining. Incubation Time: 30 minutes at RT. Recommended Positive Control: Tonsil. Western Blot: 1/100-1/500. use Human lung cell line as Positive Control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    ERCC1 (Excision Repair Cross Complementing Polypeptide-1 (ERCC1))
    别名
    ERCC1 (ERCC1 产品)
    别名
    COFS4 antibody, RAD10 antibody, UV20 antibody, Ercc-1 antibody, ercc1 antibody, T12H1.18 antibody, T12H1_18 antibody, UV REPAIR DEFICIENT 7 antibody, UVR7 antibody, ERCC excision repair 1, endonuclease non-catalytic subunit antibody, excision repair cross-complementing rodent repair deficiency, complementation group 1 antibody, DNA excision repair protein ERCC-1 antibody, nucleotide repair protein antibody, excision repair cross-complementation group 1 L homeolog antibody, excision repair cross-complementation group 1 antibody, ERCC1 antibody, Ercc1 antibody, CC1G_04546 antibody, CpipJ_CPIJ013903 antibody, PITG_13719 antibody, ercc1 antibody, ercc1.L antibody
    背景
    The mammalian ERCC1 (Excision Repair Cross Complementing) polypeptide is required for nucleotide excision repair (NER) of damaged DNA and is homologous to Saccharomyces cerevisiae RAD10, which functions in repair and mitotic intrachromosomal recombination. NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells XPG cleaves 3' of the DNA lesion while the ERCC1-XPF complex makes the 5' incision. Elevated levels of ERCC1 have also been reported in Cisplatin-resistant cells.Synonyms: COFS4, DNA excision repair protein ERCC-1, UV20
    基因ID
    2067
    NCBI登录号
    NP_001974
    UniProt
    P07992
    途径
    DNA Damage Repair, Production of Molecular Mediator of Immune Response
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