HSPG2 抗体
Quick Overview for HSPG2 抗体 (ABIN114947)
抗原
See all HSPG2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- A7L6 recognizes domain IV of the core protein of the large Heparan Sulphate Proteoglycan or Perlecan. The reactivity is independent of the galactosaminoglycan moieties. Therefore, the epitope is not sensitive to Heparitinase treatment.
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纯化方法
- Purified
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免疫原
- High molecular mass material derived from the Engelbreth-Holm-Swarm (EHS) tumor matrix containing laminin, entactin and HSPG.
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亚型
- IgG2a
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anti-Heparan Sulfate Proteoglycan 2 (HSPG2) (AA 4149-4391) antibody
HSPG2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人, 小鼠, Cow, 鱼, 猴, Pig IHC, IF, FACS, ISt, StM 宿主: 大鼠 Monoclonal A7L6 unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 人, Cow WB, IHC, ELISA, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal A71 unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) antibodyHSPG2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) (AA 25-134) antibodyHSPG2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Heparan Sulfate Proteoglycan 2 (HSPG2) (AA 524-701) antibodyHSPG2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunoprecipitation. Immunoblotting: 1/100-1/1000. Immunocytochemistry. Immunohistochemistry on frozen and paraffin-embedded tissues: 1/25-1/200 (withavidin-biotinylated horseradish peroxidase complex (ABC) as detection reagent).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing. Do not freeze working dilutions.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the original vial at 2-8 °C. After reconstitution store (in aliquots) at -20 °C.
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- HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
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别名
- HSPG2 / Perlecan
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背景
- Proteoglycans are macromolecules consisting of a variety of core proteins with covalently attached one or several polysaccharide chains of the glycosaminoglycan type (heparan sulphate, heparin, chondroitin sulphate, dermatan sulphate or keratan sulphate). At least two forms of basement membrane heparan sulphate proteoglycan (HSPG) have been identified. One with a large core protein (> 400 kD) and one with a small core protein (30 kD). The large HSPG is probably the most abundant basement membrane proteoglycan. It is located predominantly in the lamina lucida, where it forms clustered aggregates and interacts with other basement membrane components to form the matrix. In addition, it also plays a critical role in attachment of cells to the basal membrane via integrin receptors.Synonyms: Basement membrane-specific heparan sulfate proteoglycan core protein, PLC
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基因ID
- 3339
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NCBI登录号
- NP_005520
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UniProt
- P98160
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途径
- Glycosaminoglycan Metabolic Process, Lipid Metabolism
抗原
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