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HSPG2 抗体 (AA 524-701)

HSPG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042466
发货至: 中国
  • 抗原 See all HSPG2 抗体
    HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 524-701
    适用
    • 28
    • 18
    • 7
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    宿主
    • 18
    • 7
    • 6
    克隆类型
    • 19
    • 12
    多克隆
    标记
    • 21
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HSPG2 antibody is un-conjugated
    应用范围
    • 19
    • 13
    • 10
    • 9
    • 8
    • 7
    • 5
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Basement membrane-specific heparan sulfate proteoglycan core protein(HSPG2) detection. Tested with WB, IHC-P in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Basement membrane-specific heparan sulfate proteoglycan core protein(HSPG2) detection. Tested with WB, IHC-P in Human.
    Gene Name: heparan sulfate proteoglycan 2
    Protein Name: Basement membrane-specific heparan sulfate proteoglycan core protein
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human HSPG2 recombinant protein (Position: F524-K701). Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.
    亚型
    IgG
    Top Product
    Discover our top product HSPG2 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for HSPG2 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))
    别名
    HSPG2 (HSPG2 产品)
    别名
    HSPG antibody, PLC antibody, PRCAN antibody, SJA antibody, SJS antibody, SJS1 antibody, HSPG2 antibody, AI852380 antibody, Pcn antibody, Plc antibody, per antibody, Per antibody, heparan sulfate proteoglycan 2 antibody, perlecan (heparan sulfate proteoglycan 2) antibody, HSPG2 antibody, hspg2 antibody, Hspg2 antibody
    背景
    Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.

    Synonyms: Basement membrane specific heparan sulfate proteoglycan core protein antibody|Endorepellin (domain V region) antibody|Heparan Sulfate Proteoglycan antibody|Heparan sulfate proteoglycan of basement membrane antibody|HSPG 2 antibody|HSPG antibody|Hspg2 antibody|LG3 peptide antibody|Perlecan antibody|PGBM_HUMAN antibody|PLC antibody|Schwartz Jampel syndrome 1 (chondrodystrophic myotonia) antibody|SJA antibody|SJS antibody|SJS1 antibody
    基因ID
    3339
    UniProt
    P98160
    途径
    Glycosaminoglycan Metabolic Process, Lipid Metabolism
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