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CCL3 抗体

This 小鼠 单克隆 anti-CCL3 antibody (Clone 199) specifically detects CCL3 in EIA. The antibody is reactive with 人 samples.
产品编号 ABIN114725
发货至: 中国
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北京 101111
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CCL3 抗体 (ABIN114725)

抗原

See all CCL3 抗体
CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CCL3 antibody is un-conjugated

应用范围

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Enzyme Immunoassay (EIA)

克隆位点

199
  • 特异性

    This antibody reacts with recombinant MIP1 alpha. Does not show any cross reaction with other human cytokines or growth factors tested such as M-CSF, GM-CSF, IL-7, IL-8, IL-16, IL1 beta, bFGF, TGF beta, EGF, TNF alpha and EPO.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity Chromatography on Protein G.

    免疫原

    Purified recombinant Human MIP1 alpha.

    亚型

    IgG2a
  • 应用备注

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 溶解方式

    Restore with double distillated water to adjust the final concentration to 1.0 mg/mL.

    缓冲液

    0.01 M PBS, pH 7.2 without preservatives.

    储存液

    Without preservative

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原

    CCL3 (Chemokine (C-C Motif) Ligand 3 (CCL3))

    别名

    MIP1 alpha / CCL3

    背景

    Macrophage Inflammatory Protein 1 alpha (MIP1 alpha) and MIP1 beta, two closely related but distinct proteins, were originally co-purified from medium conditioned by a LPS-stimulated murine macrophage cell line. Mature mouse MIP1 alpha shares approximately 77 % and 70 % amino acid identity with human MIP1 alpha and mouse MIP1 beta, respectively. MIP1 proteins are expressed primarily in T cells, B cells, and monocytes after antigen or mitogen stimulation. Has adhesive effects on lymphocytes. MIP1 alpha can inhibit the proliferation of hematopoietic stem cells in vitro as well as in vivo. A signal transducing receptor, designated the C-C chemokine receptor-1 (C-C CKR-1) with seven transmembrane domains that bind MIP1 alpha, MIP1 beta, MCP1 and RANTES with varying affinities, has been isolated.Synonyms: C-C motif chemokine 3, CCL-3, G0/G1 switch regulatory protein 19-1, G0S19-1 protein, LD78 alpha, MIP-1-alpha, MIP1A, Macrophage Inflammatory Protein 1 alpha, SCYA3, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein

    基因ID

    6348

    NCBI登录号

    NP_002974

    UniProt

    P10147

    途径

    Cellular Response to Molecule of Bacterial Origin, Autophagy
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