CCL2 抗体
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北京 101111
Quick Overview for CCL2 抗体 (ABIN114713)
抗原
See all CCL2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Affinity Chromatography on Protein G.
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免疫原
- Purified recombinant human MCP-1
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亚型
- IgG1
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anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibody
CCL2 适用: 人, 小鼠, 猴 WB, IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 61-148) antibodyCCL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 人 WB, IHC, ELISA, IHC (p), IF, FACS 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 62-89), (C-Term) antibodyCCL2 适用: 人 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB17838 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-96) antibodyCCL2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 人, 小鼠, 猴 WB, IHC (p), IF, FACS, EIA 宿主: 小鼠 Monoclonal 2D8 unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 62-89) antibodyCCL2 适用: 人 WB, IHC, ELISA, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) antibodyCCL2 适用: 小鼠 WB, ELISA, Neut 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibodyCCL2 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Chemokine (C-C Motif) Ligand 2 (CCL2) (AA 24-99) antibodyCCL2 适用: 猕猴 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA: React with human MCP-1. Matched pair antibodies are available. Neutralizing: Tests on the ability to inhibit monocyte chemotaxis toward 1 nM recombinanthuman MCP-1 in blindwell chambers showed that the antibodies were particularly effectiveat blocking MCP-1 activity at a concentration of 0.5 μg/mL. It was also found that S-14 couldinhibit the function of native MCP-1 at concentrations similar to inhibitory doses forrecombinant MCP-1. Western Blot: Concentration of 0.1-1.0 μg/mL will allow visualization of 0.1 μg/lane ofhuman MCP-1. Concentration of 5.0 μg/mL will allow visualization of 50 μg/lane of rabbitMCP-1.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.
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浓度
- 1.0 mg/mL
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缓冲液
- 0.01 M PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- CCL2 (Chemokine (C-C Motif) Ligand 2 (CCL2))
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别名
- MCP1 / CCL2
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背景
- Monocyte chemotactic and activating factor (MCAF) is also called monocyte chemotactic protein-1 (MCP-1) and chemokine (C-C motif) ligand 2 (CCL2). It is primarily secreted by monocytes, macrophages and dendritic cells. This cytokine displays chemotactic activity for monocytes, T-cells, and basophils, but not for neutrophils or eosinophils. MCAF causes the degranulation of basophils and mast cells, and augments the activity of monocyte and macrophage. MCAF plays an important role in inflammation, angiogenesis, autoimmune diseases, renal diseases, chronic infection and granuloma formation.Synonyms: C-C motif chemokine 2, HC-11, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, SCYA2, Small-inducible cytokine A2
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基因ID
- 9606
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UniProt
- P13500
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途径
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, ER-Nucleus Signaling, Unfolded Protein Response, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
抗原
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