KRT20 抗体
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北京 101111
Quick Overview for KRT20 抗体 (ABIN114613)
抗原
See all KRT20 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
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This antibody reacts with cytokeratin polypeptide of 46 kDa in immunoblott analyses.
Cellular Localization: Cytoplasmic. -
纯化方法
- Purified
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免疫原
- Cytokeratins isolated from human micro dissected villi of human duodenal mucosa.
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亚型
- IgG2a
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应用备注
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Immunohistochemistry on Paraffin Sections: Use a dilution of 1/25-1/50 in an ABC method(30 minutes at room temperature). Formalin fixed paraffin embedded tissue sectionsrequire high temperature antigen unmasking with 10 mM Citrate buffer, pH 6.0 prior toimmunostaining. Positive Control: Skin.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- KRT20 (Keratin 20 (KRT20))
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别名
- Cytokeratin 20
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背景
- Cytokeratin 20 is a 46 kDa intermediate filament protein whose expression is restricted primarily to gastric and intestinal epithelium, urothelium, and Merkel cells. This antibody is highly specific to cytokeratin 20 and shows no cross-reactivity with other IFPs. Cytokeratin 20 is a unique type I keratin that is expressed in adenocarcinomas of the colon stomach, pancreas and bile system. It is also expressed in mucinous ovarian tumors, transitional cell carcinomas of the urinary tract, and Merkel cell carcinomas. This antibody is essentially non-reactive in squamous cell carcinomas and adenocarcinomas of the breast, lung, and endometrium, non-mucinous tumors of the ovary, and small cell carcinomas. This antibody is often used in conjunction with CK7 and other antibodies to distinguishing colon carcinomas (CK20+), from ovarian, pulmonary, and breast carcinomas.Synonyms: CK20, Cytokeratin 20, K20, KRT20, Keratin type I cytoskeletal 20, Keratin-20, Protein IT
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基因ID
- 54474
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NCBI登录号
- NP_061883
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UniProt
- P35900
抗原
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