APOA1 抗体 (HRP)
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北京 101111
Quick Overview for APOA1 抗体 (HRP) (ABIN114061)
抗原
See all APOA1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes Apo-A1 and HDL. It does not react with other plasma proteins, including albumin or immunoglobulin fractions. Does not cross react with apolipoprotein B, LDL and VLDL.
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纯化方法
- Affinity chromatography
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免疫原
- Human Apolipoprotein A1
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anti-Apolipoprotein A-I (APOA1) antibody
APOA1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-264) antibodyAPOA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-265) antibodyAPOA1 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 10-37) antibodyAPOA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 51-150) antibodyAPOA1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 20-267) antibodyAPOA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA (1/5,000 - 1/20,000). Can be used in a two site assay with BM785 bound to themicrotitre plate and ABIN114061 for detection. Higher titers can be used when TMB is usedas the substrate). Western blot (1/100 -1/600).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL (OD280)
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缓冲液
- PBS containing 50 % glycerol, 0.5 % BSA and 0.01 % Thimerosal.
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- Apolipoprotein A I (APO AI)
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背景
- Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.Synonyms: APOA1, Apo-AI, ApoA-I, ApoAI
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基因ID
- 335
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NCBI登录号
- NP_000030
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UniProt
- P02647
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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