ENOS 抗体
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北京 101111
Quick Overview for ENOS 抗体 (ABIN113627)
抗原
See all ENOS (NOS3) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Specific for the amino terminal of eNOS. It recognizes the non-myrisylated form best, but does cross-react ~50 % with the myristylated form of eNOS. Also recognizes Rat eNOS. Cross-reactivity: eNOS (2-11 Cys12): 100 % Recombinant eNOS (NOS type III): 100 % eNOS (cap-2-11Cys12): 50 % Recombinant myristylated eNOS (myristylated NOS type III): 0 % Recombinant hnNOS (NOS type I): 0 % Recombinant hiNOS (NOS type II): 0 %
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交叉反应 (详细)
- Species reactivity (tested):Human and Rat.
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免疫原
- eNOS (2-11 Cys12) covalently attached to a carrier protein
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应用备注
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Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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溶解方式
- Restore with 0.1 mL of PBS which contains 10 mg/mL BSA or with additional buffer for more dilute antibody.
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储存液
- Azide free
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!. Avoid prolonged exposure to light.
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- ENOS (NOS3) (Nitric Oxide Synthase 3 (Endothelial Cell) (NOS3))
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别名
- NOS3
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背景
- Nitric oxide synthase NOS oxidizes a guanidine nitrogen of arginine releasing nitric oxide in the form of a free radical and citrulline. Nitric oxide thus generated acts as a messenger in diverse functions including vasodilation neurotransmission, anti tumor and anti pathogenic activities. NOS is classified under three types: neuronal NOS (nNOS) or brain NOS (bNOS), inducible NOS (iNOS) or macrophage NOS (mNOS), and endothelial NOS (eNOS). eNOS is a calcium/calmodulin dependent enzyme which undergoes several post translational modifications, including acylation with myristate and palmitate, and phosphorylation on numerous residues. As with the other members of the NOS family, eNOS derives the diffusible multifunctional second messenger NO from L arginine through a series of reactions in which L citrulline is an intermediate. eNOS plays an important role in controlling vascular tone, platelet aggregation, and cardiac myocyte function.Synonyms: Constitutive NOS, EC-NOS, Endothelial NOS, NOS type III, Nitric oxide synthase, eNOS, endothelial
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基因ID
- 4846
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NCBI登录号
- NP_000594
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UniProt
- P29474
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途径
- ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Response to Molecule of Bacterial Origin, Myometrial Relaxation and Contraction, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, VEGF Signaling
抗原
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