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C3 抗体 (C-Term)

C3 适用: 人 EIA 宿主: 小鸡 Polyclonal unconjugated
产品编号 ABIN113339
发货至: 中国
  • 抗原 See all C3 抗体
    C3 (Complement Component 3 (C3))
    抗原表位
    • 15
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 87
    • 54
    • 34
    • 5
    • 4
    • 4
    • 3
    • 3
    宿主
    • 68
    • 43
    • 26
    • 8
    • 7
    • 4
    小鸡
    克隆类型
    • 122
    • 33
    多克隆
    标记
    • 65
    • 24
    • 23
    • 14
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This C3 antibody is un-conjugated
    应用范围
    • 101
    • 49
    • 37
    • 33
    • 32
    • 29
    • 29
    • 27
    • 22
    • 17
    • 13
    • 12
    • 11
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts with Human C3a and C3adesArg (67-76). It does not cross-react with C3 or C4a.
    纯化方法
    Affinity Chromatography
    免疫原
    Peptide coupled to carrier protein. The antibody was generated against the carboxy-terminal neoepitope which is not exposed on C3, allowing discrimination between C3 and C3a.
    Top Product
    Discover our top product C3 Primary Antibody
  • 应用备注
    ELISA. The titer with native human C3a was 1: 5000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    This product is photosensitive and should be protected from light
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month. DO NOT FREEZE!
  • 抗原
    C3 (Complement Component 3 (C3))
    别名
    Complement C3 (C3 产品)
    别名
    AHUS5 antibody, ARMD9 antibody, ASP antibody, C3a antibody, C3b antibody, CPAMD1 antibody, AI255234 antibody, HSE-MSF antibody, Plp antibody, C3 antibody, C3-1 antibody, sb:cb26 antibody, si:dkey-76b14.4 antibody, wu:fi34b03 antibody, wu:fj86e11 antibody, C3d antibody, asp antibody, cpamd1 antibody, c3 antibody, complement C3 antibody, complement component 3 antibody, complement component c3a, duplicate 1 antibody, complement component 3 L homeolog antibody, complement component C3 antibody, complement C3-like antibody, C3 antibody, c3a.1 antibody, c3.L antibody, LOC443475 antibody, c3 antibody, c3-1 antibody, LOC100060539 antibody
    背景
    The complement system is part of the innate immune system representing humoral defence. Activation of the complement cascade via the classical, the alternative or the Lectin pathway liberates several biologically active by-products, among them the anaphylatoxin C3a. Measurement of C3a (and C4a) in plasma or other body fluids can yield important clues about the pathological, and particularly also the inflammatory status of an organism. In serum, C3a activity is under strict control of the carboxypeptidase N. This enzyme rapidly cleaves the C-terminal arginine, thereby generating C3adesArg which shows greatly reduced biological activity as compared to C3a. Thus, the biological activity of C3a is focused mainly on its point of generation, while the degradation product C3adesArg remains relatively stable until it is cleared from the circulation.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
    基因ID
    718
    NCBI登录号
    NP_000055
    UniProt
    P01024
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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