C5 抗体
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北京 101111
Quick Overview for C5 抗体 (ABIN113312)
抗原
See all C5 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Gives a single arc when tested by IEP against fresh Human plasma. Identity has been confirmed by Double Diffusion against fresh Human plasma and a known anti-Human C5.
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纯化方法
- Ion Exchange Chromatography
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免疫原
- Human C5 purified from plasma
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亚型
- IgG
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应用备注
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Immunohistochemistry: 1/20-1/200 (as a guide). Immunodiffusion.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Glycine buffered saline, pH 7.4, containing 0.09 % Sodium Azide, 0.1 % EACA, 0.01 % Benzamidine and 1 mM EDTA
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储存液
- Sodium azide, Benzamidine, EACA
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注意事项
- This product contains Sodium azide, Benzamidine and EACA: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid multiple freeze/thaw cycles.
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- C5 (Complement Component 5 (C5))
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别名
- Complement C5
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背景
- C5 is synthesised in the liver as a single polypeptide chain. Before secretion the molecule is glycosylated and secreted into plasma as a 190 kDa glycoprotein consisting of a disulphide linked alpha-chain (111 kDa) and beta-chain (75 kDa). C5 precursor is first processed by the removal of 4 basic residues, forming two chains, beta and alpha, linked by a disulfide bond. C5 convertase activates C5 by cleaving the alpha chain, releasing C5a anaphylatoxin and generating C5b (beta chain + alpha' chain).Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, CPAMD4, Complement component 5
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基因ID
- 727
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NCBI登录号
- NP_001726
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UniProt
- P01031
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途径
- Complement System, Carbohydrate Homeostasis
抗原
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