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C3 抗体 (HRP)

C3 适用: 人 WB, EIA 宿主: 绵羊 Polyclonal HRP
产品编号 ABIN113306
发货至: 中国
  • 抗原 See all C3 抗体
    C3 (Complement Component 3 (C3))
    适用
    • 87
    • 54
    • 34
    • 5
    • 4
    • 4
    • 3
    • 3
    宿主
    • 68
    • 43
    • 26
    • 8
    • 6
    • 5
    绵羊
    克隆类型
    • 122
    • 33
    多克隆
    标记
    • 66
    • 24
    • 23
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This C3 antibody is conjugated to HRP
    应用范围
    • 100
    • 49
    • 37
    • 33
    • 32
    • 29
    • 29
    • 27
    • 22
    • 17
    • 13
    • 12
    • 11
    • 9
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects Complement 3c, a polypeptide fragment which is present in C3.
    纯化方法
    Affinity chromatography on Protein G.
    免疫原
    Complement 3c.
    Top Product
    Discover our top product C3 Primary Antibody
  • 应用备注
    Suitable for ELISA (1/200-1/800) and Western blotting (1/500-1/2000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.0 mg/mL
    缓冲液
    PBS, pH 7.2, containing 0.01 % Thiomersal as preservative.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store lyophilized product at 2 - 8 °C. Following reconstitution store at -20 °C.
  • 抗原
    C3 (Complement Component 3 (C3))
    别名
    Complement C3 (C3 产品)
    别名
    AHUS5 antibody, ARMD9 antibody, ASP antibody, C3a antibody, C3b antibody, CPAMD1 antibody, AI255234 antibody, HSE-MSF antibody, Plp antibody, C3 antibody, C3-1 antibody, sb:cb26 antibody, si:dkey-76b14.4 antibody, wu:fi34b03 antibody, wu:fj86e11 antibody, C3d antibody, asp antibody, cpamd1 antibody, c3 antibody, complement C3 antibody, complement component 3 antibody, complement component c3a, duplicate 1 antibody, complement component 3 L homeolog antibody, complement component C3 antibody, complement C3-like antibody, C3 antibody, c3a.1 antibody, c3.L antibody, LOC443475 antibody, c3 antibody, c3-1 antibody, LOC100060539 antibody
    背景
    C3 plays a central role in the activation of the complement system. Processing of C3 by C3 convertase is the central reaction in both classical and alternative complement pathways, resulting in C3a and C3b. C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates, and help to initiate the complement cascade, potentially resulting in cellular apoptosis. C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes. C3b is rapidly split in two positions by factor I and a cofactor to form iC3b (inactivated C3b) and C3f which is released. Then iC3b is slowly cleaved (possibly by factor I) to form C3c and C3dg. Defects in C3 can result in susceptibility to pyogenic infection.Synonyms: C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1, CPAMD1, Complement component 3
    基因ID
    718
    NCBI登录号
    NP_000055
    UniProt
    P01024
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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