Myeloperoxidase 抗体
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- 抗原 See all Myeloperoxidase (MPO) 抗体
- Myeloperoxidase (MPO)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Myeloperoxidase antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 纯化方法
- Ammonium sulfate precipitation and DEAE-Sephacel ion exchange chromatography.
- 免疫原
- Neutrophil Myeloperoxidase
- Top Product
- Discover our top product MPO Primary Antibody
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- 应用备注
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ELISA (>1: 4,000) and western blotting (1: 4,000 dilution gives a strong reaction to 0.3 and0.6 g antigen).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.07 mg/mL (OD280 nm, E0.1% = 1.4).
- 缓冲液
- PBS, pH 7.4, with 0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- 抗原
- Myeloperoxidase (MPO)
- 别名
- Myeloperoxidase (MPO 产品)
- 别名
- mKIAA4033 antibody, MPO antibody, LOC100335032 antibody, POX2' antibody, XPOX2' antibody, mpo antibody, mpo-A antibody, pmr-1 antibody, pmr1 antibody, pox2 antibody, xpox2 antibody, myeloperoxidase antibody, myeloperoxidase L homeolog antibody, MPO antibody, Mpo antibody, LOC100335032 antibody, mpo.L antibody
- 背景
- Myeloperoxidase is a hemoprotein that is abundantly expressed in neutrophils and secreted during their activation. Native Myeloperoxidase is represented as a covalently bound tetrameric complex of two glycosylated alpha chains (MW 59 - 64 kDa) and two unglycosylated beta chains (MW 14 kDa) with total MW 150 kDa and theoretical pI 9.2. Traditionally Myeloperoxidase was considered as a main target of anti-neutrophil cytoplasm antibodies (ANCA), the serological markers for certain systemic vasculities e.g. periarteriitis nodosa, microscopic polyarteriitis and pulmonary eosinophilic granulomatosis (Churg-Strauss syndrome). Low to moderate anti-Myeloperoxidase autoantibody levels are also reported in rheumatoid arthritis. Recently it was shown that Myeloperoxidase participates in the initiation and progression of cardiovascular disease. It possesses potent proinflammatory properties and may contribute directly to tissue injury. Now Myeloperoxidase is under consideration as one of the most promising cardiac markers.Synonyms: MPO
- 基因ID
- 9606
- UniProt
- P05164
- 途径
- Chromatin Binding
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