MAP2 抗体
Quick Overview for MAP2 抗体 (ABIN112902)
抗原
See all MAP2 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Prepared by Ammonium Sulphate fractionation
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免疫原
- Native, from brain
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anti-Microtubule-Associated Protein 2 (MAP2) (AA 260-559) antibody
MAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) antibodyMAP2 适用: 人, 小鼠, Pig WB, ELISA, ICC, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal MT-08 unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) antibodyMAP2 适用: Cow WB, ICC, IF 宿主: 小鸡 Polyclonal unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) (AA 350-400) antibodyMAP2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) antibodyMicroarray verified MAP2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB573626 unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) (N-Term) antibodyMAP2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) (AA 727-985) antibodyMAP2 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) (AA 1459-1718) antibodyMAP2 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) antibodyMicroarray verified MAP2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB2355 unconjugated
anti-Microtubule-Associated Protein 2 (MAP2) antibodyMicroarray verified MAP2 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB146071 unconjugated
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应用备注
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Immunohistochemistry on frozen sections (1: 5 - 1: 30). Western blot (Recognises mainly the MAP2 protein (280 kD) and to a lesser extent the Tauprotein (60 kD) in blotting using bovine brain extract. When testing against rat brainextract this antibody shows strong bands at 60 kD and fainter bands at the highermolecular weights. This could be due to differences in the sample preparation).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 25.5 mg/mL
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缓冲液
- PBS, pH 7.2, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- MAP2 (Microtubule-Associated Protein 2 (MAP2))
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背景
- MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2, two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.
抗原
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