APOA1 抗体
Quick Overview for APOA1 抗体 (ABIN112523)
抗原
See all APOA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Reacts with both free Apolipoprotein A1 and HDL bearing Apo-A1. Does not cross-react with ApoE, ApoB or Albumin.Aff. Const.:Kd = 3nM (for Human Apolipoprotein A1)
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纯化方法
- Affinity Chromatography on Protein A
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免疫原
- Native Human Apolipoprotein A1 from Human plasma.
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亚型
- IgG1
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anti-Apolipoprotein A-I (APOA1) antibody
APOA1 适用: 小鼠 WB, IHC, ELISA, IP 宿主: 山羊 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-264) antibodyAPOA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C13 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 25-265) antibodyAPOA1 适用: 兔 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 1-267) antibodyAPOA1 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 10-37) antibodyAPOA1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 51-150) antibodyAPOA1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC (p), FACS, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Apolipoprotein A-I (APOA1) (AA 122-267) antibodyAPOA1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C10 unconjugated
anti-Apolipoprotein A-I (APOA1) (N-Term) antibodyAPOA1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA (1/2.500 - 1/10.000). This antibody is suitable for coating microtitre plates in asandwich ELISA using catalogue number ABIN114061 for detection. Western Blot (1/250 - 1/1000). Immunohistochemistry on frozen sections (1/20 - 1/80).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore with 1.0 mL distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. We recommend that the vial is gently mixed after reconstitution.
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缓冲液
- 0.01 M Sodium Phosphate, 0.01 M Sodium Borate, 0.11 M Sodium Chloride with 1 % Mannitol and 1 % Dextran.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitve and should protected from light.
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- APOA1 (Apolipoprotein A-I (APOA1))
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别名
- Apolipoprotein A I (APO AI)
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背景
- Apolipoprotein A I promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein A I is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77 amino acids, an 18 amino acid signal peptide is removed co-translationally and a 6 amino acid propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.Synonyms: APOA1, Apo-AI, ApoA-I, ApoAI
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基因ID
- 335
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NCBI登录号
- NP_000030
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UniProt
- P02647
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途径
- Regulation of Lipid Metabolism by PPARalpha, Production of Molecular Mediator of Immune Response, Lipid Metabolism
抗原
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