TNC 抗体
(4 references)Quick Overview for TNC 抗体 (ABIN112483)
抗原
See all TNC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody recognizes tenascin, a large hexameric extracellular matrix glycoprotein.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography on Protein A.
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免疫原
- Protein preparation from a homogenate of a human mammary tumour specimen
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亚型
- IgG1
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anti-Tenascin C (TNC) (AA 513-621) antibody
TNC 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) antibodyTNC 适用: 人 WB, IP, IHC (p) 宿主: 小鼠 Monoclonal T2H5 unconjugated
anti-Tenascin C (TNC) (AA 49-181) antibodyTNC 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C4 unconjugated
anti-Tenascin C (TNC) (AA 175-342) antibodyTNC 适用: 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 1001-1100) antibodyTNC 适用: 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 49-181) antibodyTNC 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 181-290) antibodyTNC 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Tenascin C (TNC) (AA 174-621) antibodyTNC 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tenascin C (TNC) antibodyTNC 适用: 人 IHC, StM 宿主: 兔 Monoclonal TNC-2981R unconjugated Recombinant Antibody
anti-Tenascin C (TNC) antibodyTNC 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal TNC-3635 unconjugated Recombinant Antibody
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应用备注
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ELISA. Western Blotting. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: Immunohistochemical detection of Tenascinis valuable for studies of tissue differentiation and tumour growth. The antibody isexcellent for staining of paraffin-embedded tissue sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH ~7.4, 15 mM Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Immunohistochemical localization of collagen type III and type IV, laminin, tenascin and alpha-smooth muscle actin (alphaSMA) in the human liver in peliosis." in: Pathology, research and practice, Vol. 198, Issue 12, pp. 803-12, (2003) (PubMed).
: "Tenascin expression in normal, hyperplastic, dysplastic and neoplastic canine mammary tissues." in: Journal of comparative pathology, Vol. 126, Issue 1, pp. 1-8, (2002) (PubMed).
: "Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and ..." in: European journal of cancer (Oxford, England : 1990), Vol. 38, Issue 18, pp. 2362-70, (2002) (PubMed).
: "Monoclonal antibodies against transferrin. Precipitating mixtures and lack of inter-species cross-reactivity." in: Immunology letters, Vol. 4, Issue 5, pp. 231-5, (1982) (PubMed).
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: "Immunohistochemical localization of collagen type III and type IV, laminin, tenascin and alpha-smooth muscle actin (alphaSMA) in the human liver in peliosis." in: Pathology, research and practice, Vol. 198, Issue 12, pp. 803-12, (2003) (PubMed).
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- TNC (Tenascin C (TNC))
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别名
- Tenascin / TNC / HXB
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背景
- Tenascin is a high molecular ECM glycoprotein (MW app. 210-300 kDa), which contains hexamere repeat-rich single chains. It contains EGF-, Fibronectin III- and Fibronectin-similar structures. During organogenesis it is exprimed temporarily by many organs. During adulthood it reappears only in regeneration, wound healing and in stroma of various tumours. It probably has an anti-adhesive function, which plays a role during tumour speading. Tenascin is found in the central and peripheral nerve system, in smooth muscle, tendon and hyper-proliferative skin.Synonyms: Cytotactin, GMEM, GP 150-225, Glioma-associated-extracellular matrix antigen, Hexabrachion, Myotendinous antigen, Neuronectin, TN-C, Tenascin-C
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基因ID
- 3371
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NCBI登录号
- NP_002151
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UniProt
- P24821
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途径
- Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development
抗原
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