ITGA3 抗体 (Isoform 3A, N-Term)
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Quick Overview for ITGA3 抗体 (Isoform 3A, N-Term) (ABIN112368)
抗原
See all ITGA3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Isoform 3A, N-Term
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特异性
- 29A3 recognizes specifically the cytoplasmic domain of integrin subunit α3A which is present in the basal cell layer in skin, glomeruli, Bowman's capsules and distal tubuli in kidney, all vascular and capillary endothelia in brain, heart and skin, and vascular smooth muscle cells in heart. A broad species reactivity is expected because of the conserved nature of the epitope.
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纯化方法
- Purified
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免疫原
- 29A3 is a mouse monoclonal IgG1, k antibody derived by fusion of SP2/0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a synthetic peptide corresponding to the cytoplasmic domain of the integrin subunit a3A including an additional N-terminal cysteine (CRTRALYEAKRQKAEMKSQPSETERLTDDY) coupled to keyhole limpet hemocyanin.
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亚型
- IgG1
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anti-Integrin, alpha 3 (ITGA3) (AA 33-236) antibody
ITGA3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 63-248) antibodyITGA3 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 5F1D4 unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 63-248) antibodyITGA3 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7H2A11 unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 51-67), (N-Term) antibodyITGA3 适用: 人, 大鼠 WB, FACS, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (N-Term) antibodyITGA3 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 976-1025) antibodyITGA3 适用: 小鼠, Pig WB, ELISA, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) antibodyITGA3 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 168-276) antibodyITGA3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 3 (ITGA3) (AA 165-199), (N-Term) antibodyITGA3 适用: 人 WB 宿主: 兔 Polyclonal RB52792 unconjugated
anti-Integrin, alpha 3 (ITGA3) (Internal Region) antibodyITGA3 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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29A3 is suitable for Immunoblotting, Immunocytochemistry and Immunohistochemistry onfrozen tissues. Recommended dilutions: 1/100-1/200 for Immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent, and 1/100-1/1000 forImmunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.09 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing/thawing cycles and store frozen at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time, it does not show decline in activity after two weeks at 4°C.
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储存条件
- -20 °C
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储存方法
- Store lyophilized antibody at -20 °C. Aliquot the product after reconstitution to
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- ITGA3 (Integrin, alpha 3 (ITGA3))
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别名
- CD49c / ITGA3
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背景
- Integrins are a family of heterodimeric membrane glycoproteins consisting of non-covalently associated a and b subunits. More than 18 a and 8 b subunits with numerous splice variant isoforms have been identified in mammals. In general, integrins function as receptors for extracellular matrix proteins. Certain integrins can also bind to soluble ligands or to counter-receptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), resulting in aggregation of cells. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis. For integrin subunits a3 and a6, two cytoplasmic variants, A and B, have been identified.Synonyms: CD49 antigen-like family member C, FRP-2, GAPB3, Galactoprotein B3, ITGA-3, ITGAG3, Integrin alpha-3, MSK18, VLA-3 alpha chain, VLA3
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基因ID
- 3675
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NCBI登录号
- NP_002195
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UniProt
- P26006
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途径
- CXCR4-mediated Signaling Events, Integrin Complex
抗原
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