CDK6 抗体
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北京 101111
Quick Overview for CDK6 抗体 (ABIN112144)
抗原
See all CDK6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts specifically with Cdk6 kinase, which can substitute for Cdk4. Cdk6 is highly expressed in some lymphoid tumor and sarcoma cell lines (ML-1 and U-2-OS resp.). Positive staining is found in head and neck tumors.
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纯化方法
- Protein A affinity chromatography
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免疫原
- Human recombinant full-length cdk6 polypeptide
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亚型
- IgG1
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anti-Cyclin-Dependent Kinase 6 (CDK6) (AA 3-99) antibody
CDK6 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 8H4 unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyKO Validated CDK6 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyCDK6 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyCDK6 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 8H4 unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyCDK6 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Monoclonal 4F7 unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (AA 21-110) antibodyCDK6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (N-Term) antibodyCDK6 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) (pTyr24) antibodyCDK6 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyKO Validated CDK6 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB3665 unconjugated Recombinant Antibody
anti-Cyclin-Dependent Kinase 6 (CDK6) antibodyKO Validated CDK6 适用: 人 WB, FACS 宿主: 兔 Monoclonal 25GB540 unconjugated Recombinant Antibody
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应用备注
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Immunohistochemistry on frozen sections and paraffin embedded tissue (after microwavetreatment): 1: 10 for 1 - 4 h at RT or overnight at 2-8C. Western Blot. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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溶解方式
- Restore in 1 mL dist. water.
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缓冲液
- PBS, pH 7.4, containing 0.09 % NaN3, 0.5 % BSA
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C up to one week or (in aliquots) at -20 °C for longer. Centrifuge vial before opening.
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- CDK6 (Cyclin-Dependent Kinase 6 (CDK6))
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别名
- CDK6
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背景
- Cdk6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of Cdk6 first appears in mid-G1 phase, and is controlled by regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.Synonyms: Cell division protein kinase 6, PLSTIRE, Serine/threonine-protein kinase PLSTIRE
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基因ID
- 1021
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NCBI登录号
- NP_001138778
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UniProt
- Q00534
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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